QTest Labs
QTest Labs is a purpose-built CRO specializing in efficacy, cardiovascular safety, and risk assessment of pharmaceuticals and medical devices. They focus on linking discovery and pre-clinical trials to make drugs and devices safer for tomorrow, utilizing state-of-the-art science, technology, and purpose-built facilities. Their mission is to minimize lead-time and cardiovascular risk while increasing mechanistic understanding, providing comprehensive research and clear solutions.
Industries
Nr. of Employees
small (1-50)
QTest Labs
Services
Customized study design and execution to evaluate cardiovascular safety and risk of drug and device candidates using in vivo and ex vivo approaches.
Conscious, telemetered, and anesthetized in vivo assays measuring ECG, blood pressure, baroreceptor function, and other hemodynamic endpoints.
Isolated perfused heart assays to isolate direct cardiac effects, quantify coronary resistance, and measure electrophysiologic and mechanical parameters with high temporal resolution.
Evaluation of test articles in disease-relevant animal models (e.g., heart failure, ischemia, hypertension, diabetes) to better predict responses in target patient populations.
Expert interpretation of existing datasets, mechanistic analysis, and recommendations to clarify development paths and support regulatory interactions.
Conduct of GLP-compliant studies with internal quality assurance, data auditing, and validated acquisition/analysis workflows.
Customized study design and execution to evaluate cardiovascular safety and risk of drug and device candidates using in vivo and ex vivo approaches.
Conscious, telemetered, and anesthetized in vivo assays measuring ECG, blood pressure, baroreceptor function, and other hemodynamic endpoints.
Isolated perfused heart assays to isolate direct cardiac effects, quantify coronary resistance, and measure electrophysiologic and mechanical parameters with high temporal resolution.
Evaluation of test articles in disease-relevant animal models (e.g., heart failure, ischemia, hypertension, diabetes) to better predict responses in target patient populations.
Expert interpretation of existing datasets, mechanistic analysis, and recommendations to clarify development paths and support regulatory interactions.
Conduct of GLP-compliant studies with internal quality assurance, data auditing, and validated acquisition/analysis workflows.
Expertise Areas
- Cardiovascular safety pharmacology
- Preclinical efficacy testing
- Mechanistic pharmacology and toxicology
- GLP-compliant preclinical studies
Key Technologies
- Telemetry for conscious animal studies
- Langendorff isolated heart perfusion
- High-resolution electrocardiography
- Hemodynamic monitoring (inotropy/lusitropy)
News & Updates
Presentation of effects of sympathetic tone in QT interval and heart rate variability indices of Beagle Dogs, among other studies.
Collection of presentation posters on cardiovascular research topics, coming soon.
Presentation of effects of sympathetic tone in QT interval and heart rate variability indices of Beagle Dogs, among other studies.
Collection of presentation posters on cardiovascular research topics, coming soon.