PsychoGenics Inc.
PsychoGenics is a preclinical CRO specializing in CNS and orphan disorders, providing validated disease models and comprehensive preclinical capabilities to support drug discovery and development. Their mission is to help companies discover breakthroughs for severely disabling CNS and orphan disorders, reducing attrition in clinical development through high-quality, translational research and customized solutions.
Industries
Nr. of Employees
medium (51-250)
PsychoGenics Inc.
Paramus, New Jersey, United States, North America
Products
IND-ready ENT1 inhibitor candidate (licensed development program)
An investigational ENT1 transporter inhibitor candidate acquired under license for development as a potential treatment for sleep and seizure disorders and other CNS indications.
IND-ready ENT1 inhibitor candidate (licensed development program)
An investigational ENT1 transporter inhibitor candidate acquired under license for development as a potential treatment for sleep and seizure disorders and other CNS indications.
Services
Preclinical behavioral and in vivo testing
Design and execution of automated and standard rodent behavioral assays for screening, characterization and lead optimization.
EEG and pharmaco-EEG studies
Collection and ML-based analysis of EEG to generate translational biomarkers and predict therapeutic applications of CNS-active compounds.
Electrophysiology and microdialysis
Neurophysiological recordings and microdialysis sampling to assess neuronal activity and neurochemical responses to interventions.
Biomarker analysis, histology and quantitative IHC
Ex vivo biomarker quantification, tissue histology and quantitative immunohistochemistry for target engagement and pathology assessment.
PK/PD and bioanalysis
Preclinical pharmacokinetic and pharmacodynamic study design and bioanalysis to define exposure–response relationships.
Receptor occupancy and target engagement studies
Preclinical assessment of target occupancy to support mechanism-of-action characterization.
Preclinical behavioral and in vivo testing
Design and execution of automated and standard rodent behavioral assays for screening, characterization and lead optimization.
EEG and pharmaco-EEG studies
Collection and ML-based analysis of EEG to generate translational biomarkers and predict therapeutic applications of CNS-active compounds.
Electrophysiology and microdialysis
Neurophysiological recordings and microdialysis sampling to assess neuronal activity and neurochemical responses to interventions.
Biomarker analysis, histology and quantitative IHC
Ex vivo biomarker quantification, tissue histology and quantitative immunohistochemistry for target engagement and pathology assessment.
PK/PD and bioanalysis
Preclinical pharmacokinetic and pharmacodynamic study design and bioanalysis to define exposure–response relationships.
Receptor occupancy and target engagement studies
Preclinical assessment of target occupancy to support mechanism-of-action characterization.
Expertise Areas
- Phenotypic in vivo drug discovery
- Preclinical CNS pharmacology
- AI / machine-learning for pharmacology
- Translational EEG and electrophysiology
Key Technologies
- AI-driven phenotypic screening
- Computer vision for behavioral analysis
- Machine-learning classifiers trained on reference compound libraries
- Pharmaco-EEG and EEG spectral analysis