Principle Labs LLC
Principle Diagnostics is a state-of-the-art clinical and anatomic pathology laboratory founded in 2015, specializing in toxicology, molecular, and genetic testing. Licensed in over 40 states and led by an executive team with over 50 years of cumulative experience, Principle Diagnostics is committed to operational efficiency, adaptive innovation, and personalized service. The company serves a diverse clientele—including individuals, medical facilities, and research organizations—across sectors such as pain management, substance abuse, podiatry, urology, long-term care, memory care, and assisted living. Principle Diagnostics aims to be a leader in diagnostic services by continuously expanding its comprehensive test menu and upholding values of integrity, service, excellence, and innovation. The company is recognized for its strong focus on compliance, financial integrity, and the integration of advanced therapeutic management and antibiotic stewardship programs. Principle Diagnostics is also celebrated for its commitment to ethical principles, teamwork, and inspired people, striving to set an example in the industry for trust, credibility, and patient-focused outcomes. In 2024, Principle Diagnostics celebrated a decade of pioneering advancements in pharmacogenomic (PGx) testing, further cementing its role as an innovation leader in personalized medicine.
Industries
Nr. of Employees
small (1-50)
Principle Labs LLC
2550 Brodhead Road, Suite 105 Bethlehem, PA 18020
Services
Urine and oral fluid toxicology testing including presumptive screening, specimen validity testing and quantitative confirmation reporting for clinical and institutional clients.
Real-time PCR assays and multi-target panels for infectious disease detection including SARS-CoV-2 and respiratory/UTI pathogen testing.
Clinical PGx panel testing with pharmacist/PharmD overread options and provider-facing reports to support medication selection and dosing decisions.
Facility-tailored analytic reports and program support designed to measure and guide appropriate antibiotic use in skilled nursing, assisted living and hospitals.
Project-based research testing services for external partners using NGS and qPCR platforms to support product development and scientific research, including biofilm-related studies.
Remote pharmacist consults and clinical overread services to assist providers with interpretation of pharmacogenomic and infectious disease laboratory reports.
Urine and oral fluid toxicology testing including presumptive screening, specimen validity testing and quantitative confirmation reporting for clinical and institutional clients.
Real-time PCR assays and multi-target panels for infectious disease detection including SARS-CoV-2 and respiratory/UTI pathogen testing.
Clinical PGx panel testing with pharmacist/PharmD overread options and provider-facing reports to support medication selection and dosing decisions.
Facility-tailored analytic reports and program support designed to measure and guide appropriate antibiotic use in skilled nursing, assisted living and hospitals.
Project-based research testing services for external partners using NGS and qPCR platforms to support product development and scientific research, including biofilm-related studies.
Remote pharmacist consults and clinical overread services to assist providers with interpretation of pharmacogenomic and infectious disease laboratory reports.
Expertise Areas
- Clinical laboratory diagnostics
- Toxicology testing and confirmation
- Molecular diagnostics (real-time PCR/qPCR)
- Next-generation sequencing and metagenomics
Key Technologies
- Real-time PCR / qPCR
- Next-generation sequencing (NGS)
- Shotgun metagenomics
- Liquid chromatography–tandem mass spectrometry (LC-MS/MS)
News & Updates
Principle Diagnostics announces a new partnership with Dr. Brad Tice and RxGenomix, offering PharmD overread services for pharmacogenomic laboratory reports.
Spotlight on Dr. Richard Franklin, Medical Director of MVS Wound Care & Hyperbarics, Rosedale, who is Board Certified in General Surgery and specializes in Wound Care and Hyperbaric medicine.
An article discussing the importance of urine specimen validity testing in combating prescription drug misuse and subversion.
Explores how pharmacogenomics can improve patient outcomes and reduce healthcare costs by tailoring medication to individual genetic profiles.
Highlights Principle Diagnostics' long-standing commitment to innovation in pharmacogenomic testing, celebrating 10 years of excellence in PGx and its impact on personalized medicine.
Details the company's expanded opioid drug screening menu to address the opioid addiction crisis in the United States.
Principle Diagnostics announces a new partnership with Dr. Brad Tice and RxGenomix, offering PharmD overread services for pharmacogenomic laboratory reports.
Spotlight on Dr. Richard Franklin, Medical Director of MVS Wound Care & Hyperbarics, Rosedale, who is Board Certified in General Surgery and specializes in Wound Care and Hyperbaric medicine.
An article discussing the importance of urine specimen validity testing in combating prescription drug misuse and subversion.
Explores how pharmacogenomics can improve patient outcomes and reduce healthcare costs by tailoring medication to individual genetic profiles.
Highlights Principle Diagnostics' long-standing commitment to innovation in pharmacogenomic testing, celebrating 10 years of excellence in PGx and its impact on personalized medicine.
Details the company's expanded opioid drug screening menu to address the opioid addiction crisis in the United States.