Principle Diagnostics Laboratory
Principle Diagnostics is a state-of-the-art laboratory founded in 2015, specializing in toxicology, infectious diseases, genetics, molecular testing, and pharmacogenomics. Licensed in over 40 states, it provides dependable, precise, and quick laboratory services with a focus on personalized care, operational efficiency, and innovation. The company is committed to tracking the truth in every sample to ensure proper diagnosis and treatment, and it supports healthcare organizations with extensive test menus, customer service, and advanced technology. Led by an experienced executive team, including CEO Gina Mattes and other key leaders, Principle Diagnostics aims to be a leader in diagnostic services and laboratory innovation.
Industries
Nr. of Employees
small (1-50)
Principle Diagnostics Laboratory
Bethlehem, Pennsylvania, United States, North America
Products
Wound-AS PCR
Molecular diagnostics testing specifically testing the most commonly known pathogens that cause wound infections.
Wound-AS Test Menu
A comprehensive PCR test menu designed to accurately identify pathogens commonly responsible for wound infections.
Nails-AS
Comprehensive molecular testing panel for identifying fungal, bacterial, and yeast pathogens associated with nail infections.
Nails-AS PCR
Molecular diagnostics testing specifically testing the most commonly known pathogens that cause nail infections.
Gastro-AS PCR Molecular Diagnostics Testing
The Principle Diagnostics Gastro-AS PCR molecular diagnostics testing is 99.8% accurate, specifically testing the most commonly known pathogens that cause Gastrointestinal infections and reflexing against 17 resistance genes.
Next Generation Sequencing: NGS
Next Generation Sequencing testing for over 5,000 genes using the Illumina TrueSight One Expanded Sequencing Panel.
Wound-AS PCR
Molecular diagnostics testing specifically testing the most commonly known pathogens that cause wound infections.
Wound-AS Test Menu
A comprehensive PCR test menu designed to accurately identify pathogens commonly responsible for wound infections.
Nails-AS
Comprehensive molecular testing panel for identifying fungal, bacterial, and yeast pathogens associated with nail infections.
Nails-AS PCR
Molecular diagnostics testing specifically testing the most commonly known pathogens that cause nail infections.
Gastro-AS PCR Molecular Diagnostics Testing
The Principle Diagnostics Gastro-AS PCR molecular diagnostics testing is 99.8% accurate, specifically testing the most commonly known pathogens that cause Gastrointestinal infections and reflexing against 17 resistance genes.
Next Generation Sequencing: NGS
Next Generation Sequencing testing for over 5,000 genes using the Illumina TrueSight One Expanded Sequencing Panel.
Services
Specimen validity testing, presumptive screening, qualitative panels, and quantitative LC‑MS/MS confirmatory testing for urine and oral fluids.
PCR/RT‑PCR assays for SARS‑CoV‑2, respiratory pathogen panels, urine PCR for UTI/STI, and molecular testing for wound and gastro infections.
Non‑invasive genetic testing for pharmacogenomics with provider reports and optional PharmD overread and pharmacist follow‑up.
Sequencing services and related sample processing for clinical genetics and metagenomics analyses supported by bioinformatics workflows.
Custom specimen collection programs for skilled nursing, assisted living and other facilities including in‑person onboarding, training and ongoing support.
Generation of antibiotic stewardship reports for facilities to support appropriate antibiotic use and regulatory survey readiness.
Specimen validity testing, presumptive screening, qualitative panels, and quantitative LC‑MS/MS confirmatory testing for urine and oral fluids.
PCR/RT‑PCR assays for SARS‑CoV‑2, respiratory pathogen panels, urine PCR for UTI/STI, and molecular testing for wound and gastro infections.
Non‑invasive genetic testing for pharmacogenomics with provider reports and optional PharmD overread and pharmacist follow‑up.
Sequencing services and related sample processing for clinical genetics and metagenomics analyses supported by bioinformatics workflows.
Custom specimen collection programs for skilled nursing, assisted living and other facilities including in‑person onboarding, training and ongoing support.
Generation of antibiotic stewardship reports for facilities to support appropriate antibiotic use and regulatory survey readiness.
Expertise Areas
- Clinical diagnostic laboratory testing
- Toxicology testing and confirmation
- Molecular diagnostics (PCR/RT‑PCR, multiplex panels)
- Pharmacogenomics and medication guidance
Key Technologies
- Real‑time PCR / RT‑PCR
- Next‑generation sequencing (NGS)
- LC‑MS/MS (liquid chromatography–tandem mass spectrometry)
- Automated nucleic acid extraction
News & Updates
Principle Diagnostics announces a partnership with Dr. Brad Tice and RxGenomix, offering PharmD overread services for pharmacogenomic laboratory reports.
Highlighting Dr. Franklin, Medical Director of MVS Wound Care & Hyperbarics, specializing in wound care and hyperbaric medicine.
Discussing the importance of urine specimen validity testing in combating drug misuse and illicit drug use, with insights from Dr. Prakash Gupta.
Celebrating 10 years of advancements in personalized medicine and pharmacogenomics at Principle Diagnostics, highlighting milestones and future directions.
CAP Accreditation
Principle Diagnostics is officially CAP accredited, demonstrating compliance with high standards in laboratory testing.
CLIA Certification
The laboratory holds CLIA certification, ensuring quality and regulatory compliance in laboratory testing.
Principle Diagnostics announces a partnership with Dr. Brad Tice and RxGenomix, offering PharmD overread services for pharmacogenomic laboratory reports.
Highlighting Dr. Franklin, Medical Director of MVS Wound Care & Hyperbarics, specializing in wound care and hyperbaric medicine.
Discussing the importance of urine specimen validity testing in combating drug misuse and illicit drug use, with insights from Dr. Prakash Gupta.
Celebrating 10 years of advancements in personalized medicine and pharmacogenomics at Principle Diagnostics, highlighting milestones and future directions.
CAP Accreditation
Principle Diagnostics is officially CAP accredited, demonstrating compliance with high standards in laboratory testing.
CLIA Certification
The laboratory holds CLIA certification, ensuring quality and regulatory compliance in laboratory testing.