Portal


Portal Bio is a company focused on developing a universal cell engineering platform with transformative potential for research and democratizing cell therapies. Their leadership team has extensive experience in clinical cell therapy development and instrumentation, applying deep knowledge of immunology, cell biology, and delivery principles across various cell types and applications.

Industries

Biotechnology
Clinical Trials
Therapeutics
Biotechnology Research

Nr. of Employees

small (1-50)

Portal

Watertown, Massachusetts, United States


Patents

Fusion constructs and uses thereof

US-12723071-B2

View Details

Products

R&D-scale mechanical delivery instrument

Research-scale instrument designed for rapid mechanical delivery of cargo into cells for non-clinical applications, supporting high throughput and buffer flexibility.

High-throughput microwell-plate boosting system

Instrument and consumable system designed to deliver diverse cargoes across microwell plates and integrate with liquid handlers for screening workflows.

Clinical-scale cartridge system compatible with manufacturing equipment

Cartridge-based milliscale booster consumables designed to integrate with clinical and GMP-compatible cell processing platforms to enable scale-up of delivery workflows.

Single-use booster cartridges (consumables)

Consumable cartridges with a proprietary membrane optimized for delivery efficiency and cell viability, sold for a variety of cell types and cargo applications.


Services

Onboarding and white-glove technical support for instrument deployment plus consumable subscription with hardware upgrade options.

Collaborative programs and beta partnerships to integrate delivery technology with high-throughput screening workflows and clinical-scale processing equipment.

Expertise Areas

  • Mechanoporation-based intracellular delivery
  • Cell engineering for immune and stem cells
  • High-throughput assay development and screening
  • Clinical-scale cell manufacturing integration
  • Show More (4)

Key Technologies

  • Silicon membrane mechanoporation
  • High-throughput mechanical delivery systems
  • Microplate and liquid-handler compatible boosting
  • Delivery of RNA modalities (mRNA, siRNA, saRNA, circular RNA)
  • Show More (4)

News & Updates

Portal Biotechnologies has been awarded an $8 million DARPA contract to develop portable, field-deployable cell therapy production systems.

Portal Biotechnologies has been awarded an $8 million DARPA contract to develop portable cell therapy devices.

Awarded $8M DARPA contract to create field deployable cell therapy production systems.


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