Pheon Therapeutics


Pheon Therapeutics is a leading ADC (Antibody-Drug Conjugate) specialist developing next-generation ADCs for hard-to-treat cancers. Leveraging two decades of ADC experience, Pheon aims to treat difficult solid tumors with a novel pipeline of ADCs. The company employs a methodical approach to ADC development, using monoclonal antibodies against both novel and validated targets, armed with proprietary payloads or off-the-shelf linker payloads, balancing safety and efficacy. Pheon’s mission is to transition its lead asset into clinical development and build a pipeline addressing unmet medical needs across multiple cancer types. Backed by expert healthcare investors, Pheon boasts a proven leadership team in ADC engineering, clinical strategy, and business.

Industries

biotechnology
life-science
medical
therapeutics

Nr. of Employees

small (1-50)

Pheon Therapeutics

UK: Innovation House, Innovation Way, Discovery Park, Sandwich, Kent, CT13 9FF, United Kingdom; USA: 139 Main Street, Suite 201, Cambridge, MA 02142, USA


Patents

Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines

US-11912700-B2

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Cytotoxic agents

US-11466032-B2

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Anti-liferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines

US-10975074-B2

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Substituted 6a,7,8,9,10,12-hexahydrobenzo[e]pyrido[1,2-a][1,4]diazepines as anti-proliferative agents

US-10975072-B2

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Pyrridinobenzodiazepine and benzopyrridodiazecine compounds

US-10399970-B2

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Pyrrolobenzodiazepine compounds

US-9999625-B2

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Products

Pipeline of first‑in‑class and differentiated ADC assets

A privately developed pipeline comprising multiple first‑in‑class ADC candidates targeting a novel antigen overexpressed in a broad range of solid tumours; constructs utilize varied linker‑payload chemistries and are advanced through preclinical development toward clinical proof of concept.

Lead first‑in‑class ADC program entering Phase 1

Lead ADC candidate selected for first‑in‑human evaluation (Phase 1), targeting a novel antigen highly expressed in multiple solid tumour types; intended to establish clinical proof of concept.


Services

Exclusive licensing and co-development partnerships to obtain fully human antibody assets and advance them into ADC programs through preclinical development.

Expertise Areas

  • Antibody-drug conjugate (ADC) development
  • Early‑phase oncology clinical development
  • CMC strategy and biologics manufacturing
  • Antibody discovery and engineering
  • Show More (4)

Key Technologies

  • Antibody-drug conjugates (ADC)
  • Linker-payload chemistry
  • Topoisomerase‑1 inhibitor payloads
  • High drug‑antibody ratio (DAR) constructs
  • Show More (4)

News & Updates

A conference held in London from 13-16 March 2023.

A conference held in San Francisco from 9-13 January 2023.

A conference held in London from 15-17 November 2022.

An event held in London on 14 November 2022.


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