Perpetuum
Perpetuum is a biotech company dedicated to developing safe, sustainable plant-based therapeutics aimed at improving healthspan and addressing aging-related diseases. The company leverages artificial intelligence and plant biotechnology across multiple R&D platforms, including plant cell extraction, recombinant protein expression in tobacco plants, dendritic nano adjuvants, and biopolymer scaffolds. With a focus on innovation, Perpetuum aims to translate science into valuable therapeutics for the pharmaceutical, traditional Chinese medicine, nutraceutical, and cosmeceutical industries, emphasizing prevention and healthspan extension.
Industries
Nr. of Employees
small (1-50)
Perpetuum
Frans De Cortlaan 3 bus 1, 2610 Antwerpen, Belgium
Products
Plant-derived nutraceutical formulations (probiotic + plant bioactives)
Nutraceutical formulations combining clinically characterized probiotic strains with standardized plant-derived bioactives identified via in-silico screening and plant cell culture, targeting metabolic syndrome risk factors.
Bioengineered silk-based skincare proteins
Topical skincare ingredients based on functionalized spider silk–derived proteins produced in plants and formulated for skin elasticity, moisturization, and wrinkle reduction.
Dissolving microneedle patches using HP-PDRN and sacran
Dissolving microneedle patches composed of highly polymerized polydeoxyribonucleotides and sacran for transdermal delivery, tissue repair, and controlled API release for cosmetic and medical uses.
Dendritic nano-adjuvant emulsions
Size-controlled polyglycerol-based nano-adjuvant emulsions intended to stabilize antigens, co-deliver adjuvants, and enhance immune responses for vaccine formulations.
Virus-like particle vaccine candidates
Recombinant VLP-based vaccine candidates produced via plant transient expression and formulated with nano-adjuvants for enhanced immunogenicity.
Plant-derived nutraceutical formulations (probiotic + plant bioactives)
Nutraceutical formulations combining clinically characterized probiotic strains with standardized plant-derived bioactives identified via in-silico screening and plant cell culture, targeting metabolic syndrome risk factors.
Bioengineered silk-based skincare proteins
Topical skincare ingredients based on functionalized spider silk–derived proteins produced in plants and formulated for skin elasticity, moisturization, and wrinkle reduction.
Dissolving microneedle patches using HP-PDRN and sacran
Dissolving microneedle patches composed of highly polymerized polydeoxyribonucleotides and sacran for transdermal delivery, tissue repair, and controlled API release for cosmetic and medical uses.
Dendritic nano-adjuvant emulsions
Size-controlled polyglycerol-based nano-adjuvant emulsions intended to stabilize antigens, co-deliver adjuvants, and enhance immune responses for vaccine formulations.
Virus-like particle vaccine candidates
Recombinant VLP-based vaccine candidates produced via plant transient expression and formulated with nano-adjuvants for enhanced immunogenicity.
Services
R&D-to-commercial transient expression manufacturing using plant agroinfiltration, upstream growth (hydroponic/vertical farming), downstream purification, and fill/finish in classified clean rooms under cGMP processes.
In-silico neural network profiling of natural compounds against drug and disease libraries to identify candidates with desired pathway-level and safety signatures for nutraceutical and therapeutic development.
C. elegans lifespan and phenotypic screening to evaluate compound effects on ageing-related pathways and prioritize candidates for preclinical development.
Design and optimization of dendritic nano-adjuvant emulsions for vaccine antigens, including size-controlled formulations, co-adjuvant incorporation, and targeted functionalization to enhance dendritic cell uptake and lymphatic trafficking.
Design, material formulation (HP-PDRN and sacran), API loading, and prototype development of dissolving microneedle patches for cosmetic, medical device, and vaccine applications.
R&D-to-commercial transient expression manufacturing using plant agroinfiltration, upstream growth (hydroponic/vertical farming), downstream purification, and fill/finish in classified clean rooms under cGMP processes.
In-silico neural network profiling of natural compounds against drug and disease libraries to identify candidates with desired pathway-level and safety signatures for nutraceutical and therapeutic development.
C. elegans lifespan and phenotypic screening to evaluate compound effects on ageing-related pathways and prioritize candidates for preclinical development.
Design and optimization of dendritic nano-adjuvant emulsions for vaccine antigens, including size-controlled formulations, co-adjuvant incorporation, and targeted functionalization to enhance dendritic cell uptake and lymphatic trafficking.
Design, material formulation (HP-PDRN and sacran), API loading, and prototype development of dissolving microneedle patches for cosmetic, medical device, and vaccine applications.
Expertise Areas
- Plant-based recombinant protein production
- Plant cell culture and phytochemical extraction
- Vaccine adjuvant formulation and nano-carrier design
- Dissolving microneedle drug delivery
Key Technologies
- Transient expression in Nicotiana benthamiana
- Agrobacterium-mediated agroinfiltration
- Virus-like particle (VLP) production
- Dendritic polyglycerol nano-adjuvants
News & Updates
Perpetuum starts pre-clinical investigation of proprietary nano-adjuvants for vaccination strategies.
Perpetuum launches a new nutraceutical brand targeting metabolic syndrome risk factors.
Perpetuum prepares to launch the first acne treatment based on recombinant bacteriophage endolysin technology.
Perpetuum opens a new division in China for sales of cosmetic brands throughout APAC.
Perpetuum starts pre-clinical investigation of proprietary nano-adjuvants for vaccination strategies.
Perpetuum launches a new nutraceutical brand targeting metabolic syndrome risk factors.
Perpetuum prepares to launch the first acne treatment based on recombinant bacteriophage endolysin technology.
Perpetuum opens a new division in China for sales of cosmetic brands throughout APAC.