Paragon Therapeutics


Paragon Therapeutics is dedicated to discovering and developing best-in-class biologics and complex biologics for patients with high unmet needs. Founded in 2021 by Fairmount, it leverages cutting-edge science and technology to identify and propel biologics to the clinic, with a focus on rapid development and transformative therapies across various disease areas.

Industries

biotechnology
medical
therapeutics

Nr. of Employees

small (1-50)

Paragon Therapeutics

Waltham, Massachusetts, United States, North America


Patents

α4β7 integrin binding proteins and methods of use

US-12606627-B2

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IL-23 antibody compositions and methods of use

US-12522655-B2

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TL1A binding proteins and methods of use

US-12509523-B1

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TL1A binding proteins and methods of use

US-12466890-B1

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Albumin binding proteins and methods of use

US-12459994-B2

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Methods of treating gastrointestinal inflammatory disease

US-12404334-B2

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Services

End-to-end discovery and lead optimization for biologic candidates using protein and antibody engineering combined with high-throughput screening.

CMC planning and execution to generate clinical supply and data packages required for regulatory filings and first-in-human studies.

In-house drug metabolism and pharmacokinetics assessment to inform candidate selection and clinical dosing strategies.

Strategic portfolio management, alliance coordination, and licensing or spin-out enablement for assets discovered in-house.

Expertise Areas

  • Biologics discovery and engineering
  • Antibody therapeutic design and optimization
  • CMC and GMP-readiness for biologics
  • IND-enabling study execution
  • Show More (4)

Key Technologies

  • Protein engineering
  • Antibody engineering
  • High-throughput screening (HTS)
  • CMC process development
  • Show More (3)

News & Updates

Apogee Therapeutics Provides Pipeline Progress and Reports Second Quarter 2025 Financial Results.

Oruka Therapeutics Reports Second Quarter 2025 Financial Results and Provides Corporate Update.

Spyre Therapeutics Reports Second Quarter 2025 Financial Results and Provides Corporate Update.


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