Oryn Therapeutics, LLC
Oryn Therapeutics is pioneering a new frontier in drug development by emulating nature’s defense mechanisms and introducing a novel class of proprietary macrocyclic peptides designed to restore immune balance in complex and devastating diseases. The company aims to improve quality of life by creating safer, more efficacious treatments for autoimmune, chronic inflammatory diseases, drug-resistant infections, and cancer, utilizing a paradigm-changing approach based on evolutionary biology.
Industries
Nr. of Employees
small (1-50)
Oryn Therapeutics, LLC
303 Twin Dolphin Drive, Suite 600 – #1320, Redwood City, CA 94065
Products
Macrocyclic peptide therapeutic candidates (bioinspired theta-defensin analogs)
A class of bioinspired macrocyclic peptides designed to be stable, low in toxicity and immunogenicity, and synthetically accessible for treatment of autoimmune, inflammatory, infectious diseases and cancer.
Macrocyclic peptide therapeutic candidates (bioinspired theta-defensin analogs)
A class of bioinspired macrocyclic peptides designed to be stable, low in toxicity and immunogenicity, and synthetically accessible for treatment of autoimmune, inflammatory, infectious diseases and cancer.
Services
Design and conduct of Phase I clinical studies focused on safety, tolerability and PK for peptide therapeutics.
Preclinical efficacy and safety studies combined with chemistry, manufacturing and controls (CMC) activities to prepare peptide candidates for clinical testing.
Design and conduct of Phase I clinical studies focused on safety, tolerability and PK for peptide therapeutics.
Preclinical efficacy and safety studies combined with chemistry, manufacturing and controls (CMC) activities to prepare peptide candidates for clinical testing.
Expertise Areas
- Macrocyclic peptide therapeutics
- Immunomodulation
- Autoimmune and chronic inflammatory disease therapeutics
- Infectious disease therapeutics
Key Technologies
- Macrocyclic peptide engineering
- Structure-guided peptide design
- Synthetic peptide manufacturing and scale-up
- Immunogenicity and toxicity assays