On Target Laboratories, LLC


On Target Laboratories is dedicated to developing targeted intraoperative molecular imaging agents to illuminate cancer during surgery, aiming to help surgeons detect and remove more cancerous tissue for better patient outcomes. Their mission is to illuminate cancer intraoperatively so it can be removed completely, driven by core values of innovation, compassion, optimism, integrity, focus, and agility.

Industries

biotechnology
life-science
medical

Nr. of Employees

medium (51-250)

On Target Laboratories, LLC


Patents

Synthesis and composition of photodynamic therapeutic agents for the targeted treatment of cancer

US-12144874-B2

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Compositions including pafolacianine for the identification of malignant lesions

US-11986540-B2

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Methods of manufacture and synthesis of fluorescent dye compounds and uses thereof

US-11964965-B2

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CA IX-NIR dyes and their uses

US-11555821-B2

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PSMA-targeted NIR dyes and their uses

US-11484607-B2

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PSMA-targeted NIR dyes and their uses

US-10842887-B2

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Products

Folate receptor–targeted near-infrared optical imaging agent for intraoperative identification of ovarian and pulmonary lesions

An intravenously administered small-molecule ligand–dye conjugate that targets folate receptors on cancer cells and produces near-infrared fluorescence to assist surgeons in identifying malignant and non-malignant pulmonary lesions and malignant ovarian lesions during surgery.


Services

Program to provide investigational imaging agents outside clinical trials for qualifying patients, including coordination of submissions under an open IND and site/investigator training to administer the agent with required NIR camera systems.

Sponsor-side clinical development services including protocol development, site selection, GCP oversight, CRO management, monitoring, CRF/IVRS support and publication of clinical results.

Expertise Areas

  • Intraoperative molecular imaging
  • Small-molecule targeted imaging agent development
  • Clinical trial design and execution (Phase I–III)
  • Regulatory strategy and submissions (IND/NDA)
  • Show More (3)

Key Technologies

  • Near-infrared fluorescence imaging
  • Small-molecule ligand–dye conjugates
  • Folate receptor–targeted biomarker targeting
  • Intravenous infusion administration for imaging agents
  • Show More (2)

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