Nirmidas Biotech
Developer and supplier of near-infrared (NIR-I and NIR-II/SWIR) imaging systems, plasmonic gold microarray substrates, high-sensitivity multiplexed bioassays, and a portfolio of NIR dyes and nanoparticle probes for research and preclinical applications. The company provides assay development and testing services, manufactures plasmonic-modified slides and gold-coated microplates under an ISO13485 quality system, and has experience with regulatory interactions including FDA Emergency Use Authorization and CE/IVDR registration.
Industries
Nr. of Employees
small (1-50)
Nirmidas Biotech
Patents
Assays, sensing platforms, and methods for diagnosis of coronavirus infection and re-infection
US-11644465-B2
View Details
Assays, sensing platforms, and methods for diagnosis of coronavirus infection and re-infection
US-11644465-B2
View DetailsProducts
Plasmonic gold microarray slides (barcoded / nonbarcoded / customizable)
Nanostructured gold-coated microarray slides for fluorescence-enhanced multiplex assays and microarray printing; used in low-volume ELISA-like assay formats.
Gold-coated 96-well microplates and plasmonic-coated microplates
Gold-coated microplates enabling electrical conductivity, surface modification, fluorescence enhancement and surface-enhanced Raman applications; available in multiple well formats.
Dual-channel NIR confocal microarray scanner
Confocal scanner for visible and near-infrared channels (including 700–800 nm) to image tissues, cells and microarrays with high signal-to-background for multiplex assays.
Small-animal NIR-II/SWIR fluorescence imaging systems
Imaging platforms for in vivo small-animal fluorescence and bioluminescence covering visible through SWIR wavelengths (reported up to 1700 nm) with high-frame-rate video and lifetime imaging capability for deep-tissue, high-resolution imaging.
Portfolio of NIR-I / NIR-II dyes and probes (organic dyes, QDs, rare-earth NPs, SWNT, gold clusters)
A set of research-use fluorophores and nanoparticle probes with varied excitation/emission profiles (including NIR-II and NIR-IIb emitters), functional groups for conjugation, and characterized circulation/excretion behavior for in vivo/ex vivo applications.
Research-use serology and antigen/antibody kits
Assay kits and controls for multiplexed antibody (IgG/IgM/IgA) detection and antigen detection in research use formats, including small-volume assays and rapid lateral-flow formats for serology evaluation.
Plasmonic gold microarray slides (barcoded / nonbarcoded / customizable)
Nanostructured gold-coated microarray slides for fluorescence-enhanced multiplex assays and microarray printing; used in low-volume ELISA-like assay formats.
Gold-coated 96-well microplates and plasmonic-coated microplates
Gold-coated microplates enabling electrical conductivity, surface modification, fluorescence enhancement and surface-enhanced Raman applications; available in multiple well formats.
Dual-channel NIR confocal microarray scanner
Confocal scanner for visible and near-infrared channels (including 700–800 nm) to image tissues, cells and microarrays with high signal-to-background for multiplex assays.
Small-animal NIR-II/SWIR fluorescence imaging systems
Imaging platforms for in vivo small-animal fluorescence and bioluminescence covering visible through SWIR wavelengths (reported up to 1700 nm) with high-frame-rate video and lifetime imaging capability for deep-tissue, high-resolution imaging.
Portfolio of NIR-I / NIR-II dyes and probes (organic dyes, QDs, rare-earth NPs, SWNT, gold clusters)
A set of research-use fluorophores and nanoparticle probes with varied excitation/emission profiles (including NIR-II and NIR-IIb emitters), functional groups for conjugation, and characterized circulation/excretion behavior for in vivo/ex vivo applications.
Research-use serology and antigen/antibody kits
Assay kits and controls for multiplexed antibody (IgG/IgM/IgA) detection and antigen detection in research use formats, including small-volume assays and rapid lateral-flow formats for serology evaluation.
Services
Design and delivery of customized multiplexed bioassays and testing services using plasmonic-enhanced substrates and compatible imaging/readout systems for research and preclinical applications.
Design and delivery of customized multiplexed bioassays and testing services using plasmonic-enhanced substrates and compatible imaging/readout systems for research and preclinical applications.
Expertise Areas
- Near-infrared (NIR-I and NIR-II/SWIR) in vivo imaging
- Plasmonic-enhanced fluorescence diagnostics
- Multiplexed serology and protein microarray assays
- NIR dye and nanoparticle probe design
Key Technologies
- Near-infrared II (NIR-II/SWIR) fluorescence imaging (1000–1700 nm)
- Plasmonic gold microarray substrates
- Dual-channel confocal microarray scanners
- Quantum dot probes (PbS/CdS core-shell)
News & Updates
Company co-founder interviewed in Nature Photonics to discuss developments in NIR-II bioimaging and clinical potential (April 13, 2023).
Received FDA Emergency Use Authorization for a rapid COVID-19 antibody fingerstick test.
Extended shelf life for specific lots of a COVID-19 antibody combo detection kit to comply with FDA shelf-life testing updates.
Plasmonic microarray slides produced under an ISO 13485 quality system and registered under CE IVDR for device products.
Announcement of a small-animal imaging system capable of NIR-II/SWIR detection and associated NIR-II probes for preclinical research.
Entered a five-year agreement with a CLIA-certified laboratory to develop LDT serology tests using plasmonic microarray platforms.
Company co-founder interviewed in Nature Photonics to discuss developments in NIR-II bioimaging and clinical potential (April 13, 2023).
Received FDA Emergency Use Authorization for a rapid COVID-19 antibody fingerstick test.
Extended shelf life for specific lots of a COVID-19 antibody combo detection kit to comply with FDA shelf-life testing updates.
Plasmonic microarray slides produced under an ISO 13485 quality system and registered under CE IVDR for device products.
Announcement of a small-animal imaging system capable of NIR-II/SWIR detection and associated NIR-II probes for preclinical research.
Entered a five-year agreement with a CLIA-certified laboratory to develop LDT serology tests using plasmonic microarray platforms.