Nephrogen
Stanford-origin biotechnology company developing an integrated AI and experimental screening platform to design and validate viral gene-delivery vehicles with tissue-specific tropism, focused on enabling gene therapies for kidney and pancreatic diseases. The group publishes peer-reviewed and preprint research on AAV vector selection, preclinical delivery optimization, and kidney disease models.
Industries
Nr. of Employees
small (1-50)
Patents
Portable instrument for in vitro detection and quantification of biomarkers
US-10908156-B2
View Details
Portable instrument for in vitro detection and quantification of biomarkers
US-10908156-B2
View DetailsServices
Platform service combining computational design and high-throughput in vivo screening to design, prioritize, and validate viral delivery vehicles with tissue-specific tropism.
Platform service combining computational design and high-throughput in vivo screening to design, prioritize, and validate viral delivery vehicles with tissue-specific tropism.
Expertise Areas
- Gene delivery vector discovery
- AAV capsid engineering and selection
- AI-driven biological design
- Preclinical gene therapy development for kidney and pancreas
Key Technologies
- Machine learning for biological design
- High-throughput in vivo screening
- AAV vector engineering
- Barcoded library selection
News & Updates
Article on designing genome editing experiments.
Preprint describing integrated AAV optimization and delivery to kidney in murine and human tissue.
Enhancing gene transfer to renal tubules and podocytes by context-dependent selection of AAV capsids
Peer-reviewed article on AAV capsid selection improving gene transfer to kidney cell types.
Review of viral vector-based gene therapy approaches for kidney diseases.
Study demonstrating GDNF-driven tubule morphogenesis in a 3D in vitro kidney model.
Study describing use of barcoded AAV libraries to select gene therapy vectors.
Article on designing genome editing experiments.
Preprint describing integrated AAV optimization and delivery to kidney in murine and human tissue.
Enhancing gene transfer to renal tubules and podocytes by context-dependent selection of AAV capsids
Peer-reviewed article on AAV capsid selection improving gene transfer to kidney cell types.
Review of viral vector-based gene therapy approaches for kidney diseases.
Study demonstrating GDNF-driven tubule morphogenesis in a 3D in vitro kidney model.
Study describing use of barcoded AAV libraries to select gene therapy vectors.