nChroma Bio


nChroma Bio is a genetic medicines company developing programmable in vivo delivery technologies combined with gene-regulating cargos to create targeted, durable therapies. The company focuses on liver-directed and extrahepatic delivery approaches and is advancing an epigenetic editing lead candidate for chronic hepatitis B through preclinical and CTA-enabling studies.

Industries

biotechnology
medical
product-research

Nr. of Employees

medium (51-250)

nChroma Bio

Boston, Massachusetts, United States, North America


Products

CRMA-1001

A liver-directed epigenetic editor delivered via lipid nanoparticles designed to durably silence hepatitis B virus (targeting cccDNA and integrated HBV DNA) using methylation-based epigenetic modulation without DNA cutting.


Services

Strategic collaboration and partnership development

Partnering to apply modular delivery solutions and genetic cargos to joint discovery and development programs.

Expertise Areas

  • Epigenetic editing and gene regulation
  • In vivo targeted delivery
  • Liver-directed therapeutics
  • Extrahepatic delivery using engineered particles
  • Show More (4)

Key Technologies

  • Lipid nanoparticles (LNPs)
  • Engineered virus-like particles (eVLP/DLVR)
  • Epigenetic editors (DNA methylation-based)
  • Ribonucleoprotein (RNP) delivery of gene editors (base editors, prime editors, CRISPR/Cas)
  • Show More (3)

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