Napo Pharmaceuticals, Inc
Napo Pharmaceuticals is dedicated to developing and commercializing prescription medicines that support the comfort, quality of life, and dignity of people with treatment-related GI distress, specifically overactive bowel. Their mission focuses on providing relief for symptoms such as chronic diarrhea, urgency, and incontinence, through innovative medicines harvested responsibly from rainforest plants. They are actively conducting clinical trials, including a Phase 3 pivotal trial of Mytesi® (crofelemer) for chemotherapy-induced overactive bowel, and supporting investigator-initiated studies for rare diseases like short bowel syndrome and microvillus inclusion disease. The company emphasizes environmental sustainability and social responsibility, sharing benefits with local communities.
Industries
Nr. of Employees
small (1-50)
Napo Pharmaceuticals, Inc
San Francisco, California, United States, North America
Products
crofelemer (oral botanical-derived chloride channel inhibitor)
An orally administered botanical-derived therapeutic that modulates secretory chloride ion channels in the gastrointestinal tract to address chronic diarrhea and overactive bowel symptoms.
crofelemer (oral botanical-derived chloride channel inhibitor)
An orally administered botanical-derived therapeutic that modulates secretory chloride ion channels in the gastrointestinal tract to address chronic diarrhea and overactive bowel symptoms.
Services
Pivotal clinical trial sponsorship and management
Sponsorship and operational management of late-stage clinical trials for follow-on therapeutic indications, including protocol implementation and enrollment oversight.
Support for investigator-initiated trials
Provision of operational and clinical support resources for externally initiated proof-of-concept studies across multiple regions.
Pharmacovigilance and product inquiry call center
Telephone and email service for product information, adverse event reports, and product complaint handling.
Sustainability and benefit-sharing program
Programs and practices for responsible harvesting of plant materials with environmental stewardship and benefit-sharing with local communities.
Commercial development for prescription supportive-care medicines
Activities to bring prescription supportive-care therapeutics to market, including regulatory, commercial, and distribution readiness.
Pivotal clinical trial sponsorship and management
Sponsorship and operational management of late-stage clinical trials for follow-on therapeutic indications, including protocol implementation and enrollment oversight.
Support for investigator-initiated trials
Provision of operational and clinical support resources for externally initiated proof-of-concept studies across multiple regions.
Pharmacovigilance and product inquiry call center
Telephone and email service for product information, adverse event reports, and product complaint handling.
Sustainability and benefit-sharing program
Programs and practices for responsible harvesting of plant materials with environmental stewardship and benefit-sharing with local communities.
Commercial development for prescription supportive-care medicines
Activities to bring prescription supportive-care therapeutics to market, including regulatory, commercial, and distribution readiness.
Expertise Areas
- Clinical trial management
- Supportive-care therapeutics for gastrointestinal disorders
- Natural product / botanical drug development
- Pharmacovigilance and safety reporting
Key Technologies
- Pivotal clinical trial execution
- Pharmacovigilance systems and AE reporting
- Botanical extraction and plant-derived material sourcing
- Ion channel modulation therapeutics