Napo Pharmaceuticals, Inc.


Napo Pharmaceuticals is dedicated to developing and commercializing prescription medicines that support the comfort, quality of life, and dignity of people with treatment-related GI distress, specifically overactive bowel. Their mission focuses on providing relief for symptoms such as chronic diarrhea, urgency, and incontinence, through innovative medicines harvested responsibly from rainforest plants. They are actively conducting clinical trials, including a Phase 3 pivotal trial of Mytesi® (crofelemer) for chemotherapy-induced overactive bowel, and supporting investigator-initiated studies for rare diseases like short bowel syndrome and microvillus inclusion disease. The company emphasizes environmental sustainability and social responsibility, sharing benefits with local communities.

Industries

biotechnology
collaboration
health-care
medical

Nr. of Employees

small (1-50)

Napo Pharmaceuticals, Inc.

200 Pine Street, Suite 400, San Francisco, CA 94104


Patents

Methods and compositions for treating congenital diarrhea disorder

US-11857510-B2

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Methods and compositions for treating bile acid diarrhea, diarrhea associated with small intestine resection or gallbladder removal, and short bowel syndrome

US-11779564-B2

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Methods and compositions for treating chemotherapy-induced diarrhea

US-11389424-B2

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Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer

US-9987250-B2

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Method for treatment of diarrhea-predominant irritable bowel syndrome

US-9980938-B2

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Methods and compositions for treating HIV-associated diarrhea

US-9585868-B2

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Products

crofelemer (oral botanical-derived chloride channel inhibitor)

An orally administered botanical-derived therapeutic that modulates secretory chloride ion channels in the gastrointestinal tract to address chronic diarrhea and overactive bowel symptoms.


Services

Sponsorship and operational management of late-stage clinical trials for follow-on therapeutic indications, including protocol implementation and enrollment oversight.

Provision of operational and clinical support resources for externally initiated proof-of-concept studies across multiple regions.

Telephone and email service for product information, adverse event reports, and product complaint handling.

Programs and practices for responsible harvesting of plant materials with environmental stewardship and benefit-sharing with local communities.

Activities to bring prescription supportive-care therapeutics to market, including regulatory, commercial, and distribution readiness.

Expertise Areas

  • Clinical trial management
  • Supportive-care therapeutics for gastrointestinal disorders
  • Natural product / botanical drug development
  • Pharmacovigilance and safety reporting
  • Show More (3)

Key Technologies

  • Pivotal clinical trial execution
  • Pharmacovigilance systems and AE reporting
  • Botanical extraction and plant-derived material sourcing
  • Ion channel modulation therapeutics
  • Show More (3)

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