Metabolic Solutions Development


MSDC is a drug discovery and development company investigating new molecular targets and developing novel therapeutics to treat metabolic diseases associated with age-related mitochondrial dysfunction, especially insulin resistance and type 2 diabetes. The company's mission is to develop drugs that will have positive effects on healthcare outcomes, focusing on innovative treatments for metabolic diseases, neurodegeneration, and related conditions.

Industries

biopharma
biotechnology
life-science

Nr. of Employees

small (1-50)

Metabolic Solutions Development

161 E Michigan Ave., 4th Floor Kalamazoo, MI 49007


Patents

PPAR-sparing compounds for the treatment of metabolic diseases

US-9562012-B2

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Synthesis for thiazolidinedione compounds

US-8946435-B2

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Synthesis for thiazolidinedione compounds

US-8895748-B2

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Thiazolidinedione analogues

US-8629159-B2

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Products

MSDC-0160

Oral small-molecule modulator of a mitochondrial protein complex developed as an insulin sensitizer and investigated for neurodegenerative and metabolic indications; studied in Phase 2a trials in Alzheimer’s disease and a Phase 2b study in type 2 diabetes.

MSDC-0602 / MSDC-0602K (clinical development program)

Oral small-molecule insulin-sensitizing compound developed for metabolic liver disease (NASH) and type 2 diabetes; advanced into randomized Phase 2 clinical evaluation (EMMINENCE trial for NASH).

Expertise Areas

  • Clinical trial management
  • Small-molecule therapeutics development
  • Mitochondrial-targeted drug discovery
  • Translational medicine and biomarker development
  • Show More (4)

Key Technologies

  • Photoaffinity labeling and radioligand binding
  • Protein purification and recombinant expression
  • Gene knockdown experiments
  • Metabolomics
  • Show More (3)

News & Updates

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