Mayfield Fund
Mayfield is a multi-stage venture capital firm that provides equity funding and operational support to technology and deep‑tech companies. The firm invests across seed through growth stages, operates dedicated vehicles for sector-focused programs (example: a seed vehicle for generative AI), offers board and product-level guidance, and publishes sector playbooks and founder resources. Mayfield emphasizes hands‑on, founder‑focused support across areas including AI, enterprise software, semiconductors, healthcare, diagnostics, and hardware/wearables.
Mayfield Fund
Menlo Park, California, United States, North America
Services
Direct equity investment (Seed through Growth)
Provides capital across stages including seed, Series A–D and growth; operates dedicated vehicles (example: a $250M seed vehicle for AI founders) and participates as lead or follow-on investor.
Board‑level and operational guidance
Board service and partner engagement focused on product strategy, go‑to‑market, fundraising and governance; hands‑on partner support and recurring operational counsel to founders.
Founder education, sector playbooks and content
Publishes practitioner‑focused content, thematic research, playbooks and run workshops and roundtables on topics such as wearables, quantum computing, AI, digital health and board best practices.
Network introductions and corporate partnerships
Facilitates introductions to potential customers, corporate partners, strategic acquirers and follow‑on investors; supports strategic meetings and partnership development.
Talent and recruiting advisory
Advises on hiring strategy and team‑building, connects founders to recruiting networks and designs programs to attract entry‑level and senior operational talent.
Product, data and platform guidance for hardware and data infrastructure companies
Operational advice covering manufacturing and supply‑chain decisions (including North America vs. Asia tradeoffs), device and sensor strategy, data instrumentation and metrics for device‑as‑a‑service businesses, API/SDK and platform roadmap planning.
Direct equity investment (Seed through Growth)
Provides capital across stages including seed, Series A–D and growth; operates dedicated vehicles (example: a $250M seed vehicle for AI founders) and participates as lead or follow-on investor.
Board‑level and operational guidance
Board service and partner engagement focused on product strategy, go‑to‑market, fundraising and governance; hands‑on partner support and recurring operational counsel to founders.
Founder education, sector playbooks and content
Publishes practitioner‑focused content, thematic research, playbooks and run workshops and roundtables on topics such as wearables, quantum computing, AI, digital health and board best practices.
Network introductions and corporate partnerships
Facilitates introductions to potential customers, corporate partners, strategic acquirers and follow‑on investors; supports strategic meetings and partnership development.
Talent and recruiting advisory
Advises on hiring strategy and team‑building, connects founders to recruiting networks and designs programs to attract entry‑level and senior operational talent.
Product, data and platform guidance for hardware and data infrastructure companies
Operational advice covering manufacturing and supply‑chain decisions (including North America vs. Asia tradeoffs), device and sensor strategy, data instrumentation and metrics for device‑as‑a‑service businesses, API/SDK and platform roadmap planning.
Portfolio
Initially a dental marketplace; pivoted to serve self‑insured employers and licensed SaaS to carriers; raised ~$54M and later merged with/was acquired by Cigna.
#Healthcare / Digital health / Dental marketplace
Develops CRISPR‑based detection methods for DNA/RNA diagnostics; holds an exclusive license from UC Berkeley.
#Diagnostics / Precision medicine / CRISPR-based diagnostics
Provides real‑time operational guidance for hospital environments.
#Healthcare operations / Hospital workflow software
Enables rapid single‑cell DNA mapping for clinicians and researchers.
#Genomics / Single‑cell DNA analysis
Built cloud‑integrated storage appliances; acquired by Microsoft in 2012 and integrated with Azure offerings.
#Cloud‑integrated storage / Enterprise infrastructure
Initially a dental marketplace; pivoted to serve self‑insured employers and licensed SaaS to carriers; raised ~$54M and later merged with/was acquired by Cigna.
#Healthcare / Digital health / Dental marketplace
Develops CRISPR‑based detection methods for DNA/RNA diagnostics; holds an exclusive license from UC Berkeley.
#Diagnostics / Precision medicine / CRISPR-based diagnostics
Provides real‑time operational guidance for hospital environments.
#Healthcare operations / Hospital workflow software
Enables rapid single‑cell DNA mapping for clinicians and researchers.
#Genomics / Single‑cell DNA analysis
Built cloud‑integrated storage appliances; acquired by Microsoft in 2012 and integrated with Azure offerings.
#Cloud‑integrated storage / Enterprise infrastructure