MassBiologics
MassBiologics is a non-profit, FDA-licensed manufacturer of vaccines and biologic products, dedicated to improving public health through research, development, and production of biologics including vaccines, plasma derivatives, and monoclonal antibodies. Located in Boston, it has a mission of creating medicines for better lives and a vision to be a center of excellence in biologic medicines and technologies, serving both local and global communities.
Industries
Nr. of Employees
large (251-1000)
MassBiologics
Boston, Massachusetts, United States, North America
Products
Tetanus and Diphtheria (Td) toxoid vaccine (adsorbed)
Licensed vaccine product manufactured and distributed nationwide for routine immunization.
Licensed and investigational monoclonal antibody therapeutics
Portfolio of developed and partnered monoclonal antibody candidates and licensed antibody therapeutics for infectious and other indications; includes products at investigational and commercial stages.
0055VCT, rLV.EF1.Tet3G-9, 1 x 20 uL
Lentiviral vector expressing Tet3G transactivator under the EF1 promoter.
rLV.EF1.ZsGreen1-9
Lentiviral vector expressing ZsGreen1 fluorescent reporter under the EF1 promoter.
rLV.EF1.mCherry-9
Lentiviral vector expressing mCherry fluorescent reporter under the EF1 promoter.
0011VCT, rLV.EF1.AmCyan1-9, 3 x 20 uL
Lentiviral vector expressing AmCyan1 fluorescent reporter under the EF1 promoter.
0012VCT, rLV.EF1.ZsYellow1-9, 3 x 20 uL
Lentiviral vector expressing ZsYellow1 fluorescent reporter under the EF1 promoter.
rLV.EF1.tdTomato-9
Lentiviral vector expressing tdTomato fluorescent reporter under the EF1 promoter.
rLV.EF1.AcGFP1-Tubulin-9
Organelle marker lentiviral vector expressing AcGFP1-Tubulin fusion protein for microtubule labeling.
rLV.EF1.AcGFP1-Endo-9
Organelle marker lentiviral vector for endosome labeling.
rLV.EF1.AcGFP1-Actin-9
Organelle marker lentiviral vector expressing AcGFP1-Actin fusion protein for actin cytoskeleton labeling.
0023VCT, rLV.EF1.mCherry-Nuc-9, 3 x 20 uL
Lentiviral vector expressing mCherry nuclear organelle marker under the EF1 promoter.
0016VCT, rLV.EF1.AcGFP1-Nuc-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 nuclear organelle marker under the EF1 promoter.
0019VCT, rLV.EF1.AcGFP1-Mem-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 cell membrane marker under the EF1 promoter.
0021VCT, rLV.EF1.mCherry-Tubulin-9, 3 x 20 uL
Lentiviral vector expressing mCherry-Tubulin organelle marker under the EF1 promoter.
0022VCT, rLV.EF1.mCherry-Golgi-9, 3 x 20 uL
Lentiviral vector expressing mCherry-Golgi organelle marker under the EF1 promoter.
0020VCT, rLV.EF1.mCherry-Actin-9, 3 x 20 uL
Lentiviral vector expressing mCherry-Actin organelle marker under the EF1 promoter.
0015VCT, rLV.EF1.AcGFP1-Golgi-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1-Golgi organelle marker under the EF1 promoter.
0017VCT, rLV.EF1.AcGFP1-Mito-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 mitochondrial organelle marker under the EF1 promoter.
0024VCT, rLV.EF1.mCherry-Mito-9, 3 x 20 uL
Lentiviral vector expressing mCherry mitochondrial organelle marker under the EF1 promoter.
0025VCT, rLV.EF1.mCherry-ER-9, 3 x 20 uL
Lentiviral vector expressing mCherry endoplasmic reticulum marker under the EF1 promoter.
0026VCT, rLV.EF1.mCherry-Mem-9, 3 x 20 uL
Lentiviral vector expressing mCherry cell membrane marker under the EF1 promoter.
0018VCT, rLV.EF1.AcGFP1-Endo-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 endoplasmic reticulum marker under the EF1 promoter.
RLP-CRE-ZsGreen1-11
Cre recombinase lentiviral vector expressing Cre and ZsGreen1 reporter.
0059VCT, RLP-CRE-11, 2 x 20 uL
Cre recombinase expressing lentiviral vector.
K.lactis Protein Expression Kit
K. lactis Protein Expression Kit - 1 set.
K. lactis GG799 Competent Cells
K. lactis GG799 Competent Cells - 5 reactions.
pT7-IRES Myc-N DNA
T7 expression plasmid vector with N-terminal Myc tag and IRES.
pT7-IRES His-N DNA
T7 expression plasmid vector with N-terminal His tag and IRES.
pT7-IRES His-C DNA
T7 expression plasmid vector with C-terminal His tag and IRES.
T-Vector
TA cloning vector for efficient cloning of PCR products.
T-Vector pMD™20
TA cloning vector for efficient cloning of PCR products.
pBR322 DNA
Standard cloning plasmid vector pBR322.
Alkaline Phosphatase (Calf Intestine)
Calf intestinal alkaline phosphatase for dephosphorylation of DNA and RNA.
Alkaline Phosphatase (E coli C75)
Enzyme for removing 5' phosphate groups from DNA and RNA.
Alkaline Phosphatase (Shrimp)
Heat-labile shrimp alkaline phosphatase for dephosphorylating DNA and RNA.
pUC 118 EcoR I/BAP
EcoR I digested and BAP dephosphorylated pUC118 vector.
pUC 118 Hinc II/BAP
Hinc II digested and BAP dephosphorylated pUC118 vector.
pUC 118 DNA
Phagemid vector pUC118.
pGEM-T
Comprehensive system containing vector and control reagents for cloning PCR products.
pGEM(R)-T Easy Vector System I
Standard vector system for cloning PCR products.
pKF 18k-2 DNA
Plasmid vector pKF 18k-2.
1227B, BspQ I, 2,500 U
BspQ I molecular biology restriction enzyme.
Bln I (Avr II)
Molecular biology restriction enzyme.
pUC 19 DNA
Standard high-copy-number cloning plasmid vector pUC19.
pUC 18 DNA
Standard high-copy-number cloning plasmid vector pUC18.
3118, M13 mp18 RF DNA, 10 ug
M13 mp18 RF plasmid DNA.
T4 DNA Ligase
DNA ligase reagent for joining DNA strands.
2040A, T4 DNA Polymerase, 100 Units
T4 DNA Polymerase reagent.
E. coli DNA Ligase
DNA ligase that joins nicked double-stranded DNA.
NEBridge Golden Gate Assembly Kit (BsmBI-v2)
NEBridge Golden Gate Assembly Kit (BsmBI-v2) - 100 reactions.
NEBridge Golden Gate Enzyme Kit (BsaI-HFv2)
NEBridge Golden Gate Enzyme Kit (BsaI-HFv2) - 20 reactions.
2410B, S1 Nuclease, 100,000 Units
S1 Nuclease for single-stranded DNA and RNA cleavage.
Exonuclease I
Single-stranded DNA specific exonuclease.
Lambda DNA
Lambda phage genomic DNA standard.
PhiX174 RF I DNA
PhiX174 replicative form I DNA.
BL21(DE3) Competent E. coli
BL21(DE3) Competent E. coli - 20 x 0.05 ml.
BL21 Competent E. coli
BL21 Competent E. coli - 20 x 0.05 ml.
T4 RNA Ligase
RNA ligase reagent for joining single-stranded RNA or DNA.
3071, Thermus Thermophilus HB8 Genomic DNA Solution, 2 ug
Thermus Thermophilus HB8 genomic DNA solution.
Phusion® HF Buffer Pack
Phusion HF Buffer Pack - 6 ml.
Phusion® GC Buffer Pack
Phusion GC Buffer Pack - 6 ml.
NEBuffer Set(EcoRI, DpnII)
NEBuffer Set (EcoRI/SspI, DpnII) - 1.25 ml each.
NEBuffer Set (r1.1, r2.1, r3.1 & rCutSmart)
NEBuffer Set (r1.1, r2.1, r3.1 & rCutSmart) - 1.25 ml each.
NEBuffer™ r3.1
NEBuffer r3.1 - 5 ml.
NEBuffer™ r2.1
NEBuffer r2.1 - 5 ml.
NEBuffer™ 1
NEBuffer 1 - 5 ml.
NEBuffer™ 3
NEBuffer 3 - 5 ml.
NEBuffer™ 4
NEBuffer 4 - 5 ml.
NEB® 10-beta Competent E. coli (High Efficiency)
NEB 10-beta Competent E. coli (High Efficiency) - 20 x 0.05 ml.
BAL 31 Nuclease
Exo- and endonuclease specific for single- and double-stranded DNA.
Klenow Fragment (Large Fragment E. coli DNA Polymerase I)
E. coli DNA Polymerase I reagent for nick translation and second-strand synthesis.
2140A, Klenow Fragment (Large Fragment E. coli DNA Polymerase I), 200 Units
Klenow Fragment of E. coli DNA Polymerase I.
2140AK, Klenow Fragment for Sequencing (Large Fragment E. coli DNA Polymerase I), 200 Units
Klenow Fragment for DNA sequencing applications.
Exonuclease III
Exonuclease that digests double-stranded DNA unidirectionally from 3' ends.
2170B, Exonuclease III, 25,000 Units
Exonuclease III reagent.
Terminal Deoxynucleotidyl Transferase
Template-independent polymerase that catalyzes the addition of deoxynucleotides to the 3' terminus of DNA.
pRI 101-AN DNA
Plant transformation vector.
pRI 101-ON DNA
Plant transformation vector.
pRI 201-AN DNA
Plant transformation vector.
pRI 201-ON DNA
Plant transformation vector.
T7 RNA Polymerase ver.2.0
High-yield T7 RNA polymerase for in vitro transcription.
Recombinant DNase I (RNase-free)
RNase-free recombinant DNase I for digesting DNA.
2420B, Mung Bean Nuclease, 10,000 Units
Mung Bean Nuclease for single-stranded nucleic acid digestion.
Micrococcal Nuclease
Nuclease that digests single- and double-stranded DNA and RNA.
Q5® High-Fidelity PCR Kit
Q5 High-Fidelity PCR Kit - 200 reactions.
SP6 RNA Polymerase
RNA polymerase specific for SP6 promoter sequences.
Poly(A) Polymerase
Template-independent polymerase that adds AMP to the 3' ends of RNA.
2180A, Poly(A) Polymerase, 20 Units
Poly(A) Polymerase enzyme.
PrimeScript™ Reverse Transcriptase
High-efficiency reverse transcriptase for cDNA synthesis.
Wizard(R) MagneSil(R) Plasmid Purification System
Magnetic bead-based system for high-throughput plasmid DNA purification.
Wizard MagneSil Tfx(TM) System
Magnetic particle-based system for genomic DNA purification.
Wizard(R) MagneSil(R) Seq'ing Reaction Clean-Up System
Magnetic bead-based system for DNA sequencing reaction clean-up.
Uracil DNA Glycosylase (UNG), Heat-Labile
Heat-labile UNG for carryover prevention in PCR.
Ribonuclease H
Endoribonuclease that specifically degrades RNA in RNA-DNA hybrids.
Standard Taq
Standard Taq (Mg-free) Reaction Buffer Pack - 6 ml.
Wizard(R) SV 96 Plasmid DNA Purification System
96-well format system for plasmid DNA purification.
Wizard(R) Genomic DNA Purification Kit
Genomic DNA purification kit available in various isolation capacities.
Wizard(R) SV Genomic DNA Purification System
Spin-column system for genomic DNA isolation from various sample types.
Wizard(R) HMW DNA Extraction Kit
Kit for the isolation of high molecular weight (HMW) genomic DNA.
DNase I-XT Reaction Buffer
DNase I-XT Reaction Buffer - 6 ml. New product release in 2024.
DNase I Reaction Buffer
Reaction buffer for DNase I - 6 ml.
mRNA Cap 2'-O-Methyltransferase
Enzyme that methylates the 2'-O position of the penultimate nucleotide at the 5' end of capped mRNA.
Cryonase™ Cold-Active Nuclease
Cold-active nuclease that is active at low temperatures.
NEBNext® Second Strand Synthesis (dNTP-free) Reaction Buffer
NEBNext Second Strand Synthesis (dNTP-free) Reaction Buffer - 0.4 ml.
Recombinant RNase Inhibitor
Inhibitor of common ribonucleases to protect RNA integrity.
2315A, Recombinant RNase Inhibitor ver.2.0, 5,000 U
Recombinant RNase Inhibitor version 2.0.
AMV Reverse Transcriptase XL for RT-PCR
Reverse transcriptase optimized for high-temperature and difficult template RT-PCR.
Reverse Transcription System
System for synthesizing first-strand cDNA.
mRNA Interferase™-MazF
Endoribonuclease that cleaves single-stranded RNA at specific ACA sequences.
Pyrophosphatase (inorganic)
Enzyme that catalyzes the hydrolysis of inorganic pyrophosphate to orthophosphate.
MagneSil(R) Red
Paramagnetic particle suspension for molecular biology applications.
MagneSil(R) Blue
Paramagnetic particles for automated or manual nucleic acid isolation.
Vaccinia Capping Enzyme
Enzyme for adding a cap structure to the 5' end of in vitro transcribed mRNA.
ReliaPrep(TM) DNA Clean-up and Concentration System
System for clean-up and concentration of DNA from various reactions.
ReliaPrep(TM) gDNA Tissue Miniprep System
System for rapid isolation of genomic DNA from tissue samples.
ReliaPrep(TM) FFPE gDNA Miniprep System
System for genomic DNA isolation from formalin-fixed, paraffin-embedded tissue.
Binding Buffer (BBF)
Binding buffer for nucleic acid extraction protocols.
Binding Buffer 1 (BBD)
Binding buffer component for specialized extraction kits.
Viral Vector CDMO Services
Development and cGMP production services for viral vector-based therapeutics, supporting AAV, AdV, and Lenti virus using adherent, suspension-adapted, and insect cell lines.
Biopharmaceutical CDMO Services
Contract development and manufacturing services for monoclonal antibodies and recombinant protein therapeutics expressed in mammalian cell culture, supported by facilities in Mattapan and Fall River.
Aseptic Fill Finish
cGMP manufacturing services offering clinical and commercial product filling with low line loss and capacities up to 250,000 units.
Cell Line & Culture Development Services
Custom cell line and culture development services from vector construction to harvest, including batch-fed process development and optimization for therapeutic candidates using mammalian cell lines such as CHO, NS0, and HEK.
CMO Services
New drug development and manufacturing for clinical trials providing a variety of Development, Analytical and Manufacturing services including bacterial and mammalian cell based expression systems, downstream processing, and aseptic fill-finish operations.
Cell Culture-Bulk Drug Substance cGMP Manufacturing Services
MassBiologics facilities support cGMP biopharmaceutical production in mammalian cell culture, offering upstream processing in accordance with FDA and EU standards.
Human Cell-Free Protein Expression System
Cell-free protein expression kit derived from human cells.
Large scale AAV manufacturing: 2x 200L XDR200 bioreactors
Large scale AAV production utilizing 200L XDR200 bioreactors and AKTA pilot for upstream and downstream processes with pre-designed, gamma-irradiated tubing sets in a closed disposable system.
Small scale antibody production from transduced cell pools with client supplied DNA for antibody gene sequences
Small scale antibody production from transduced cell pools with client supplied DNA for antibody gene sequences using MBL2 CHO cells.
Medium scale AAV manufacturing: 10L XDR10 or 25L wave bioreactor
Medium scale production manufactured in 10L XDR10 bioreactor or 25L Wave bioreactor for pre-200L runs, process testing, and preliminary sample production.
Processing development for large scale AAV Manufacturing
Optimization of large scale production for upstream and downstream processes to achieve maximum yield and full/empty ratio, developing SOPs for GMP production transfer.
Promega Catalog Items
Discounts on most items from the Promega catalog with free overnight shipping.
Generation of stable clones with client provided DNA
Generation of stable clones using client provided DNA with electroporation into MBL2 CHO cells and clone selection.
Takara Bio Catalog Items
Discount pricing on many products from TaKaRa Bio with free shipping and dry ice on all orders.
cGMP biopharmaceutical manufacturing and quality services
Comprehensive cGMP quality systems and biopharmaceutical manufacturing services for licensed and investigational products.
pBApo-EF1alpha Pur DNA
Mammalian expression plasmid with EF1-alpha promoter and Puromycin resistance.
AAV capsid DNA engineering for Insect cell production
Engineering of capsid DNA for production of AAV in an insect cell system with full analysis including silver staining, CE-SDS, EM, and comparison to mammalian cell produced capsid.
pDONR 221
Donor vector used in MultiSite Gateway recombination reactions.
MultiSite Gateway Three Fragment Vector Construction Kit
A kit utilizing Gateway Technology to simultaneously clone multiple DNA fragments.
pDONR P4-P1R
Donor vector used in MultiSite Gateway recombination reactions.
pDONR P2R-P3
Donor vector used in MultiSite Gateway recombination reactions.
pDEST R4-R3 Vector II
Destination vector for MultiSite Gateway recombination reactions.
pHSG 298 DNA
Low-copy-number cloning plasmid vector pHSG298.
pHSG 299 DNA
Low-copy-number cloning plasmid vector pHSG299.
Antibody production in 10L bioreactor from stable clone, ≤ 10g produced
Antibody production in a 60L bioreactor with a 40L working volume, producing up to 40g.
pBApo-CMV Pur DNA
Mammalian expression plasmid with CMV promoter and Puromycin resistance.
NEB Catalog Items
17% discount off list price on all New England Biolabs items with free overnight shipping.
ThermoFisher Catalog Items
Discount pricing on many items from ThermoFisher with free overnight shipping.
BP Clonase II Enzyme Mix
Enzyme mix for BP recombination reaction between attB-flanked DNA fragment and attP donor vector.
pMS/GW control plasmid
Control plasmid included in the MultiSite Gateway kit.
LR Clonase II Plus Enzyme Mix
Enzyme mix for MultiSite Gateway LR recombination reactions.
NEB® PCR Cloning Kit (Without Competent Cells)
NEB PCR Cloning Kit (Without Competent Cells) - 20 reactions.
pUC 119 DNA
Phagemid vector pUC119.
Working Cell Banking
Creation of a Working Cell Bank from a single Master Cell Bank vial for subsequent use in product production.
Master Cell Banking
Establishment of a Master Cell Bank produced in accordance with regulatory standards (21 CFR 610) for recombinant therapeutics.
Lemo21(DE3) Competent E. coli
Lemo21(DE3) Competent E. coli - 12 x 0.05 ml.
NEB® Turbo Competent E. coli (High Efficiency)
NEB Turbo Competent E. coli (High Efficiency) - 20 x 0.05 ml.
NiCo21(DE3) Competent E. coli
NiCo21(DE3) Competent E. coli - 20 x 0.05 ml.
T7 Express lysY/Iq Competent E. coli (High Efficiency)
T7 Express lysY/Iq Competent E. coli (High Efficiency) - 6 x 0.2 ml.
NEB® 5-alpha F Iq Competent E. coli (High Efficiency)
NEB 5-alpha F Iq Competent E. coli (High Efficiency) - 20 x 0.05 ml.
Azura Genomics Catalog Items
Discount pricing on items from the Azura Genomics catalog with free shipping.
NEBExpress® Competent E. coli (High Efficiency)
NEBExpress Iq Competent E. coli (High Efficiency) - 6 x 0.2 ml.
SHuffle® Express Competent E.coli
SHuffle Express Competent E. coli - 12 x 0.05 ml.
NEB® Stable Competent E. coli (High Efficiency)
NEB Stable Competent E. coli (High Efficiency) - 20 x 0.05 ml.
2130B, DNA Polymerase I (E.coli), 2,500 Units
DNA Polymerase I from E. coli.
2542A, T7 RNA Polymerase, HQ, 200,000 U
High quality T7 RNA Polymerase for in vitro transcription.
pRI 910 DNA
Plant transformation binary vector.
pRI 909 DNA
Plant transformation binary vector.
Xcellerex™ 200L
Xcellerex XDR single-use bioreactor systems provide scalable and robust stirred-tank performance for up to 2000 L in both cGMP and non-cGMP environments.
Agilent Catalog Items
Discount pricing on most items from the Agilent catalog with free overnight shipping.
2490A, NucleoGone™ Endonuclease, 25,000 Units
NucleoGone Endonuclease for nucleic acid removal.
Quality Control Services
MassBiologics' Quality Control group performs or oversees the testing and release of all raw materials, cell banks, in-process, product release, and stability samples, as well as routine monitoring of cleanroom environments and cGMP clean utilities.
Formulation Development Services
Formulation development services for biological products, including high concentration antibody formulations, excipient screening, and pre-formulation accelerated stress studies.
NEB Cloning Competent E. coli Sampler
NEB Cloning Competent E. coli Sampler - 8 x 0.05 ml.
One Shot TOP10 Chemically Competent E. coli
Chemically competent E. coli for routine cloning and plasmid propagation.
2561A, PrimeCap™ T7 RNA Polymerase (low dsRNA), HQ, 200,000 U
High quality PrimeCap T7 RNA Polymerase yielding low dsRNA during transcription.
Quick Blunting and Quick Ligation Kits
Quick Blunting and Quick Ligation Kits - 20 reactions.
Roche Kapa Division Catalog Items
Discount pricing on items from the Roche Kapa Biosystems catalog with free shipping.
rProteinase K Solution AOF
Animal-origin free recombinant Proteinase K solution for general digestion.
2481A, Faustovirus Capping Enzyme (S17), HQ, 25000 U
High quality Faustovirus Capping Enzyme (S17).
GoScript(TM) Reverse Transcriptase
Recombinant reverse transcriptase for first-strand cDNA synthesis.
rCutSmart™ Buffer
rCutSmart Buffer - 5 ml.
Access RT-PCR System
System for performing reverse transcription and PCR in a single buffer system.
T4 DNA Ligase Reaction Buffer
Reaction buffer for T4 DNA Ligase - 5 ml.
Library Efficiency DH5α Chemically Competent Cells
Chemically competent cells for transformation.
T4 Polynucleotide Kinase Reaction Buffer
Reaction buffer for T4 Polynucleotide Kinase - 4 ml.
Phusion® High-Fidelity PCR Kit
Phusion High-Fidelity PCR Kit - 200 reactions.
ImProm-II(TM) Reverse Transcriptase
Reverse transcriptase enzyme optimized for sensitive RT-PCR applications.
Bio-Rad Catalog Items
Discount pricing on most items from the Bio-Rad catalog with free shipping.
Analytical Method Development
MassBiologics provides analytical method development and optimization services as part of a larger program or as a stand-alone service, ranging from early discovery to robust methods transferred to Quality Control for cGMP activities.
Qiagen Catalog Items
Discount pricing on items from the Qiagen catalog with free shipping.
NEBNext Quick Ligation Reaction Buffer (5X)
NEBNext Quick Ligation Reaction Buffer (5X) - 2 ml.
Taq DNA Ligase Reaction Buffer
Reaction buffer for Taq DNA Ligase - 6 ml.
Q5® Reaction Buffer Pack
Q5 Reaction Buffer Pack - 6 ml.
StickTogether™ DNA Ligase Buffer
StickTogether DNA Ligase Buffer - 2 ml.
Xcellerex XDR 10 single-use stirred-tank bioreactor
The single-use Xcellerex XDR 10 is a flexible, stirred-tank bioreactor system suitable for use in process development, small-scale production, and process troubleshooting.
Alkaline Protease Solution
Enzyme solution for protein digestion and sample processing.
Nuclease-free Water
Nuclease-free Water - 100 ml.
Exonuclease I Reaction Buffer
Reaction buffer for Exonuclease I - 6 ml.
ThermoPol® Reaction Buffer Pack
ThermoPol Reaction Buffer Pack - 6 ml.
PureYield(TM) Plasmid Miniprep System
System for rapid purification of plasmid DNA from E. coli.
AccessQuick(TM) RT-PCR System
Master mix system for fast reverse transcription and PCR amplification.
Wave 50 Bioreactor System
The WAVE Bioreactor system features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures.
Cell Lysis Buffer (CLD)
Buffer for cell lysis applications.
Magnesium Chloride (MgCl2) Solution
Magnesium Chloride (MgCl2) Solution - 6 ml.
Recombinant Albumin, Molecular Biology Grade
Recombinant Albumin, Molecular Biology Grade - 12 mg.
Resin
Purification resin for molecular biology applications.
LunaScript® Multiplex One-Step RT-PCR Kit
LunaScript Multiplex One-Step RT-PCR Kit - 250 reactions.
Elution Buffer
Buffer solution for eluting purified nucleic acids.
Antarctic Phosphatase Reaction Buffer
Reaction buffer for Antarctic Phosphatase - 6 ml.
4/40 Wash Solution
Wash solution component for specialized purification protocols.
Millipore Sigma Catalog Items
Discount pricing on many items from the Millipore Sigma catalog with free shipping.
Neutralization Solution (NSB)
Buffer solution for nucleic acid purification workflows.
Magnesium Chloride Solution, 25mM
Magnesium chloride solution for PCR and enzymatic optimization.
AKTA Pure
ÄKTA pure protein purification system is a flexible and intuitive chromatography system designed to meet purification challenges in research applications.
ÄKTA pilot 600 chromatography system
ÄKTA pilot 600 is a compact bench-top chromatography system with a wide flow and pressure range. It suits both production of technical batches and scale-up studies as well as small-scale production of GMP-grade material.
Column Wash Solution (CWA)
Wash solution component for purification columns.
Magnesium Sulfate (MgSO4) Solution
Magnesium Sulfate (MgSO4) Solution - 6 ml.
Maxwell(R) HT 96 gDNA Blood
High-throughput system for genomic DNA extraction from blood samples.
AKTA Avant
ÄKTA avant is a preparative protein purification chromatography system designed for fast and secure development of scalable methods and processes.
Blue Protein Loading Dye
Blue Protein Loading Dye - 8 ml.
Corning Tissue Culture Products, Buffers, and FBS
Tissue culture products, buffers, and fetal bovine serum with discount pricing and free shipping.
Tetanus Toxoid for Research
Tetanus Toxoid designated for research use (not for use in humans).
National Diagnostics Catalog Items
List pricing on items from the National Diagnostics catalog with free shipping.
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Tetanus and Diphtheria (Td) toxoid vaccine (adsorbed)
Licensed vaccine product manufactured and distributed nationwide for routine immunization.
Licensed and investigational monoclonal antibody therapeutics
Portfolio of developed and partnered monoclonal antibody candidates and licensed antibody therapeutics for infectious and other indications; includes products at investigational and commercial stages.
0055VCT, rLV.EF1.Tet3G-9, 1 x 20 uL
Lentiviral vector expressing Tet3G transactivator under the EF1 promoter.
rLV.EF1.ZsGreen1-9
Lentiviral vector expressing ZsGreen1 fluorescent reporter under the EF1 promoter.
rLV.EF1.mCherry-9
Lentiviral vector expressing mCherry fluorescent reporter under the EF1 promoter.
0011VCT, rLV.EF1.AmCyan1-9, 3 x 20 uL
Lentiviral vector expressing AmCyan1 fluorescent reporter under the EF1 promoter.
0012VCT, rLV.EF1.ZsYellow1-9, 3 x 20 uL
Lentiviral vector expressing ZsYellow1 fluorescent reporter under the EF1 promoter.
rLV.EF1.tdTomato-9
Lentiviral vector expressing tdTomato fluorescent reporter under the EF1 promoter.
rLV.EF1.AcGFP1-Tubulin-9
Organelle marker lentiviral vector expressing AcGFP1-Tubulin fusion protein for microtubule labeling.
rLV.EF1.AcGFP1-Endo-9
Organelle marker lentiviral vector for endosome labeling.
rLV.EF1.AcGFP1-Actin-9
Organelle marker lentiviral vector expressing AcGFP1-Actin fusion protein for actin cytoskeleton labeling.
0023VCT, rLV.EF1.mCherry-Nuc-9, 3 x 20 uL
Lentiviral vector expressing mCherry nuclear organelle marker under the EF1 promoter.
0016VCT, rLV.EF1.AcGFP1-Nuc-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 nuclear organelle marker under the EF1 promoter.
0019VCT, rLV.EF1.AcGFP1-Mem-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 cell membrane marker under the EF1 promoter.
0021VCT, rLV.EF1.mCherry-Tubulin-9, 3 x 20 uL
Lentiviral vector expressing mCherry-Tubulin organelle marker under the EF1 promoter.
0022VCT, rLV.EF1.mCherry-Golgi-9, 3 x 20 uL
Lentiviral vector expressing mCherry-Golgi organelle marker under the EF1 promoter.
0020VCT, rLV.EF1.mCherry-Actin-9, 3 x 20 uL
Lentiviral vector expressing mCherry-Actin organelle marker under the EF1 promoter.
0015VCT, rLV.EF1.AcGFP1-Golgi-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1-Golgi organelle marker under the EF1 promoter.
0017VCT, rLV.EF1.AcGFP1-Mito-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 mitochondrial organelle marker under the EF1 promoter.
0024VCT, rLV.EF1.mCherry-Mito-9, 3 x 20 uL
Lentiviral vector expressing mCherry mitochondrial organelle marker under the EF1 promoter.
0025VCT, rLV.EF1.mCherry-ER-9, 3 x 20 uL
Lentiviral vector expressing mCherry endoplasmic reticulum marker under the EF1 promoter.
0026VCT, rLV.EF1.mCherry-Mem-9, 3 x 20 uL
Lentiviral vector expressing mCherry cell membrane marker under the EF1 promoter.
0018VCT, rLV.EF1.AcGFP1-Endo-9, 3 x 20 uL
Lentiviral vector expressing AcGFP1 endoplasmic reticulum marker under the EF1 promoter.
RLP-CRE-ZsGreen1-11
Cre recombinase lentiviral vector expressing Cre and ZsGreen1 reporter.
0059VCT, RLP-CRE-11, 2 x 20 uL
Cre recombinase expressing lentiviral vector.
K.lactis Protein Expression Kit
K. lactis Protein Expression Kit - 1 set.
K. lactis GG799 Competent Cells
K. lactis GG799 Competent Cells - 5 reactions.
pT7-IRES Myc-N DNA
T7 expression plasmid vector with N-terminal Myc tag and IRES.
pT7-IRES His-N DNA
T7 expression plasmid vector with N-terminal His tag and IRES.
pT7-IRES His-C DNA
T7 expression plasmid vector with C-terminal His tag and IRES.
T-Vector
TA cloning vector for efficient cloning of PCR products.
T-Vector pMD™20
TA cloning vector for efficient cloning of PCR products.
pBR322 DNA
Standard cloning plasmid vector pBR322.
Alkaline Phosphatase (Calf Intestine)
Calf intestinal alkaline phosphatase for dephosphorylation of DNA and RNA.
Alkaline Phosphatase (E coli C75)
Enzyme for removing 5' phosphate groups from DNA and RNA.
Alkaline Phosphatase (Shrimp)
Heat-labile shrimp alkaline phosphatase for dephosphorylating DNA and RNA.
pUC 118 EcoR I/BAP
EcoR I digested and BAP dephosphorylated pUC118 vector.
pUC 118 Hinc II/BAP
Hinc II digested and BAP dephosphorylated pUC118 vector.
pUC 118 DNA
Phagemid vector pUC118.
pGEM-T
Comprehensive system containing vector and control reagents for cloning PCR products.
pGEM(R)-T Easy Vector System I
Standard vector system for cloning PCR products.
pKF 18k-2 DNA
Plasmid vector pKF 18k-2.
1227B, BspQ I, 2,500 U
BspQ I molecular biology restriction enzyme.
Bln I (Avr II)
Molecular biology restriction enzyme.
pUC 19 DNA
Standard high-copy-number cloning plasmid vector pUC19.
pUC 18 DNA
Standard high-copy-number cloning plasmid vector pUC18.
3118, M13 mp18 RF DNA, 10 ug
M13 mp18 RF plasmid DNA.
T4 DNA Ligase
DNA ligase reagent for joining DNA strands.
2040A, T4 DNA Polymerase, 100 Units
T4 DNA Polymerase reagent.
E. coli DNA Ligase
DNA ligase that joins nicked double-stranded DNA.
NEBridge Golden Gate Assembly Kit (BsmBI-v2)
NEBridge Golden Gate Assembly Kit (BsmBI-v2) - 100 reactions.
NEBridge Golden Gate Enzyme Kit (BsaI-HFv2)
NEBridge Golden Gate Enzyme Kit (BsaI-HFv2) - 20 reactions.
2410B, S1 Nuclease, 100,000 Units
S1 Nuclease for single-stranded DNA and RNA cleavage.
Exonuclease I
Single-stranded DNA specific exonuclease.
Lambda DNA
Lambda phage genomic DNA standard.
PhiX174 RF I DNA
PhiX174 replicative form I DNA.
BL21(DE3) Competent E. coli
BL21(DE3) Competent E. coli - 20 x 0.05 ml.
BL21 Competent E. coli
BL21 Competent E. coli - 20 x 0.05 ml.
T4 RNA Ligase
RNA ligase reagent for joining single-stranded RNA or DNA.
3071, Thermus Thermophilus HB8 Genomic DNA Solution, 2 ug
Thermus Thermophilus HB8 genomic DNA solution.
Phusion® HF Buffer Pack
Phusion HF Buffer Pack - 6 ml.
Phusion® GC Buffer Pack
Phusion GC Buffer Pack - 6 ml.
NEBuffer Set(EcoRI, DpnII)
NEBuffer Set (EcoRI/SspI, DpnII) - 1.25 ml each.
NEBuffer Set (r1.1, r2.1, r3.1 & rCutSmart)
NEBuffer Set (r1.1, r2.1, r3.1 & rCutSmart) - 1.25 ml each.
NEBuffer™ r3.1
NEBuffer r3.1 - 5 ml.
NEBuffer™ r2.1
NEBuffer r2.1 - 5 ml.
NEBuffer™ 1
NEBuffer 1 - 5 ml.
NEBuffer™ 3
NEBuffer 3 - 5 ml.
NEBuffer™ 4
NEBuffer 4 - 5 ml.
NEB® 10-beta Competent E. coli (High Efficiency)
NEB 10-beta Competent E. coli (High Efficiency) - 20 x 0.05 ml.
BAL 31 Nuclease
Exo- and endonuclease specific for single- and double-stranded DNA.
Klenow Fragment (Large Fragment E. coli DNA Polymerase I)
E. coli DNA Polymerase I reagent for nick translation and second-strand synthesis.
2140A, Klenow Fragment (Large Fragment E. coli DNA Polymerase I), 200 Units
Klenow Fragment of E. coli DNA Polymerase I.
2140AK, Klenow Fragment for Sequencing (Large Fragment E. coli DNA Polymerase I), 200 Units
Klenow Fragment for DNA sequencing applications.
Exonuclease III
Exonuclease that digests double-stranded DNA unidirectionally from 3' ends.
2170B, Exonuclease III, 25,000 Units
Exonuclease III reagent.
Terminal Deoxynucleotidyl Transferase
Template-independent polymerase that catalyzes the addition of deoxynucleotides to the 3' terminus of DNA.
pRI 101-AN DNA
Plant transformation vector.
pRI 101-ON DNA
Plant transformation vector.
pRI 201-AN DNA
Plant transformation vector.
pRI 201-ON DNA
Plant transformation vector.
T7 RNA Polymerase ver.2.0
High-yield T7 RNA polymerase for in vitro transcription.
Recombinant DNase I (RNase-free)
RNase-free recombinant DNase I for digesting DNA.
2420B, Mung Bean Nuclease, 10,000 Units
Mung Bean Nuclease for single-stranded nucleic acid digestion.
Micrococcal Nuclease
Nuclease that digests single- and double-stranded DNA and RNA.
Q5® High-Fidelity PCR Kit
Q5 High-Fidelity PCR Kit - 200 reactions.
SP6 RNA Polymerase
RNA polymerase specific for SP6 promoter sequences.
Poly(A) Polymerase
Template-independent polymerase that adds AMP to the 3' ends of RNA.
2180A, Poly(A) Polymerase, 20 Units
Poly(A) Polymerase enzyme.
PrimeScript™ Reverse Transcriptase
High-efficiency reverse transcriptase for cDNA synthesis.
Wizard(R) MagneSil(R) Plasmid Purification System
Magnetic bead-based system for high-throughput plasmid DNA purification.
Wizard MagneSil Tfx(TM) System
Magnetic particle-based system for genomic DNA purification.
Wizard(R) MagneSil(R) Seq'ing Reaction Clean-Up System
Magnetic bead-based system for DNA sequencing reaction clean-up.
Uracil DNA Glycosylase (UNG), Heat-Labile
Heat-labile UNG for carryover prevention in PCR.
Ribonuclease H
Endoribonuclease that specifically degrades RNA in RNA-DNA hybrids.
Standard Taq
Standard Taq (Mg-free) Reaction Buffer Pack - 6 ml.
Wizard(R) SV 96 Plasmid DNA Purification System
96-well format system for plasmid DNA purification.
Wizard(R) Genomic DNA Purification Kit
Genomic DNA purification kit available in various isolation capacities.
Wizard(R) SV Genomic DNA Purification System
Spin-column system for genomic DNA isolation from various sample types.
Wizard(R) HMW DNA Extraction Kit
Kit for the isolation of high molecular weight (HMW) genomic DNA.
DNase I-XT Reaction Buffer
DNase I-XT Reaction Buffer - 6 ml. New product release in 2024.
DNase I Reaction Buffer
Reaction buffer for DNase I - 6 ml.
mRNA Cap 2'-O-Methyltransferase
Enzyme that methylates the 2'-O position of the penultimate nucleotide at the 5' end of capped mRNA.
Cryonase™ Cold-Active Nuclease
Cold-active nuclease that is active at low temperatures.
NEBNext® Second Strand Synthesis (dNTP-free) Reaction Buffer
NEBNext Second Strand Synthesis (dNTP-free) Reaction Buffer - 0.4 ml.
Recombinant RNase Inhibitor
Inhibitor of common ribonucleases to protect RNA integrity.
2315A, Recombinant RNase Inhibitor ver.2.0, 5,000 U
Recombinant RNase Inhibitor version 2.0.
AMV Reverse Transcriptase XL for RT-PCR
Reverse transcriptase optimized for high-temperature and difficult template RT-PCR.
Reverse Transcription System
System for synthesizing first-strand cDNA.
mRNA Interferase™-MazF
Endoribonuclease that cleaves single-stranded RNA at specific ACA sequences.
Pyrophosphatase (inorganic)
Enzyme that catalyzes the hydrolysis of inorganic pyrophosphate to orthophosphate.
MagneSil(R) Red
Paramagnetic particle suspension for molecular biology applications.
MagneSil(R) Blue
Paramagnetic particles for automated or manual nucleic acid isolation.
Vaccinia Capping Enzyme
Enzyme for adding a cap structure to the 5' end of in vitro transcribed mRNA.
ReliaPrep(TM) DNA Clean-up and Concentration System
System for clean-up and concentration of DNA from various reactions.
ReliaPrep(TM) gDNA Tissue Miniprep System
System for rapid isolation of genomic DNA from tissue samples.
ReliaPrep(TM) FFPE gDNA Miniprep System
System for genomic DNA isolation from formalin-fixed, paraffin-embedded tissue.
Binding Buffer (BBF)
Binding buffer for nucleic acid extraction protocols.
Binding Buffer 1 (BBD)
Binding buffer component for specialized extraction kits.
Viral Vector CDMO Services
Development and cGMP production services for viral vector-based therapeutics, supporting AAV, AdV, and Lenti virus using adherent, suspension-adapted, and insect cell lines.
Biopharmaceutical CDMO Services
Contract development and manufacturing services for monoclonal antibodies and recombinant protein therapeutics expressed in mammalian cell culture, supported by facilities in Mattapan and Fall River.
Aseptic Fill Finish
cGMP manufacturing services offering clinical and commercial product filling with low line loss and capacities up to 250,000 units.
Cell Line & Culture Development Services
Custom cell line and culture development services from vector construction to harvest, including batch-fed process development and optimization for therapeutic candidates using mammalian cell lines such as CHO, NS0, and HEK.
CMO Services
New drug development and manufacturing for clinical trials providing a variety of Development, Analytical and Manufacturing services including bacterial and mammalian cell based expression systems, downstream processing, and aseptic fill-finish operations.
Cell Culture-Bulk Drug Substance cGMP Manufacturing Services
MassBiologics facilities support cGMP biopharmaceutical production in mammalian cell culture, offering upstream processing in accordance with FDA and EU standards.
Human Cell-Free Protein Expression System
Cell-free protein expression kit derived from human cells.
Large scale AAV manufacturing: 2x 200L XDR200 bioreactors
Large scale AAV production utilizing 200L XDR200 bioreactors and AKTA pilot for upstream and downstream processes with pre-designed, gamma-irradiated tubing sets in a closed disposable system.
Small scale antibody production from transduced cell pools with client supplied DNA for antibody gene sequences
Small scale antibody production from transduced cell pools with client supplied DNA for antibody gene sequences using MBL2 CHO cells.
Medium scale AAV manufacturing: 10L XDR10 or 25L wave bioreactor
Medium scale production manufactured in 10L XDR10 bioreactor or 25L Wave bioreactor for pre-200L runs, process testing, and preliminary sample production.
Processing development for large scale AAV Manufacturing
Optimization of large scale production for upstream and downstream processes to achieve maximum yield and full/empty ratio, developing SOPs for GMP production transfer.
Promega Catalog Items
Discounts on most items from the Promega catalog with free overnight shipping.
Generation of stable clones with client provided DNA
Generation of stable clones using client provided DNA with electroporation into MBL2 CHO cells and clone selection.
Takara Bio Catalog Items
Discount pricing on many products from TaKaRa Bio with free shipping and dry ice on all orders.
cGMP biopharmaceutical manufacturing and quality services
Comprehensive cGMP quality systems and biopharmaceutical manufacturing services for licensed and investigational products.
pBApo-EF1alpha Pur DNA
Mammalian expression plasmid with EF1-alpha promoter and Puromycin resistance.
AAV capsid DNA engineering for Insect cell production
Engineering of capsid DNA for production of AAV in an insect cell system with full analysis including silver staining, CE-SDS, EM, and comparison to mammalian cell produced capsid.
pDONR 221
Donor vector used in MultiSite Gateway recombination reactions.
MultiSite Gateway Three Fragment Vector Construction Kit
A kit utilizing Gateway Technology to simultaneously clone multiple DNA fragments.
pDONR P4-P1R
Donor vector used in MultiSite Gateway recombination reactions.
pDONR P2R-P3
Donor vector used in MultiSite Gateway recombination reactions.
pDEST R4-R3 Vector II
Destination vector for MultiSite Gateway recombination reactions.
pHSG 298 DNA
Low-copy-number cloning plasmid vector pHSG298.
pHSG 299 DNA
Low-copy-number cloning plasmid vector pHSG299.
Antibody production in 10L bioreactor from stable clone, ≤ 10g produced
Antibody production in a 60L bioreactor with a 40L working volume, producing up to 40g.
pBApo-CMV Pur DNA
Mammalian expression plasmid with CMV promoter and Puromycin resistance.
NEB Catalog Items
17% discount off list price on all New England Biolabs items with free overnight shipping.
ThermoFisher Catalog Items
Discount pricing on many items from ThermoFisher with free overnight shipping.
BP Clonase II Enzyme Mix
Enzyme mix for BP recombination reaction between attB-flanked DNA fragment and attP donor vector.
pMS/GW control plasmid
Control plasmid included in the MultiSite Gateway kit.
LR Clonase II Plus Enzyme Mix
Enzyme mix for MultiSite Gateway LR recombination reactions.
NEB® PCR Cloning Kit (Without Competent Cells)
NEB PCR Cloning Kit (Without Competent Cells) - 20 reactions.
pUC 119 DNA
Phagemid vector pUC119.
Working Cell Banking
Creation of a Working Cell Bank from a single Master Cell Bank vial for subsequent use in product production.
Master Cell Banking
Establishment of a Master Cell Bank produced in accordance with regulatory standards (21 CFR 610) for recombinant therapeutics.
Lemo21(DE3) Competent E. coli
Lemo21(DE3) Competent E. coli - 12 x 0.05 ml.
NEB® Turbo Competent E. coli (High Efficiency)
NEB Turbo Competent E. coli (High Efficiency) - 20 x 0.05 ml.
NiCo21(DE3) Competent E. coli
NiCo21(DE3) Competent E. coli - 20 x 0.05 ml.
T7 Express lysY/Iq Competent E. coli (High Efficiency)
T7 Express lysY/Iq Competent E. coli (High Efficiency) - 6 x 0.2 ml.
NEB® 5-alpha F Iq Competent E. coli (High Efficiency)
NEB 5-alpha F Iq Competent E. coli (High Efficiency) - 20 x 0.05 ml.
Azura Genomics Catalog Items
Discount pricing on items from the Azura Genomics catalog with free shipping.
NEBExpress® Competent E. coli (High Efficiency)
NEBExpress Iq Competent E. coli (High Efficiency) - 6 x 0.2 ml.
SHuffle® Express Competent E.coli
SHuffle Express Competent E. coli - 12 x 0.05 ml.
NEB® Stable Competent E. coli (High Efficiency)
NEB Stable Competent E. coli (High Efficiency) - 20 x 0.05 ml.
2130B, DNA Polymerase I (E.coli), 2,500 Units
DNA Polymerase I from E. coli.
2542A, T7 RNA Polymerase, HQ, 200,000 U
High quality T7 RNA Polymerase for in vitro transcription.
pRI 910 DNA
Plant transformation binary vector.
pRI 909 DNA
Plant transformation binary vector.
Xcellerex™ 200L
Xcellerex XDR single-use bioreactor systems provide scalable and robust stirred-tank performance for up to 2000 L in both cGMP and non-cGMP environments.
Agilent Catalog Items
Discount pricing on most items from the Agilent catalog with free overnight shipping.
2490A, NucleoGone™ Endonuclease, 25,000 Units
NucleoGone Endonuclease for nucleic acid removal.
Quality Control Services
MassBiologics' Quality Control group performs or oversees the testing and release of all raw materials, cell banks, in-process, product release, and stability samples, as well as routine monitoring of cleanroom environments and cGMP clean utilities.
Formulation Development Services
Formulation development services for biological products, including high concentration antibody formulations, excipient screening, and pre-formulation accelerated stress studies.
NEB Cloning Competent E. coli Sampler
NEB Cloning Competent E. coli Sampler - 8 x 0.05 ml.
One Shot TOP10 Chemically Competent E. coli
Chemically competent E. coli for routine cloning and plasmid propagation.
2561A, PrimeCap™ T7 RNA Polymerase (low dsRNA), HQ, 200,000 U
High quality PrimeCap T7 RNA Polymerase yielding low dsRNA during transcription.
Quick Blunting and Quick Ligation Kits
Quick Blunting and Quick Ligation Kits - 20 reactions.
Roche Kapa Division Catalog Items
Discount pricing on items from the Roche Kapa Biosystems catalog with free shipping.
rProteinase K Solution AOF
Animal-origin free recombinant Proteinase K solution for general digestion.
2481A, Faustovirus Capping Enzyme (S17), HQ, 25000 U
High quality Faustovirus Capping Enzyme (S17).
GoScript(TM) Reverse Transcriptase
Recombinant reverse transcriptase for first-strand cDNA synthesis.
rCutSmart™ Buffer
rCutSmart Buffer - 5 ml.
Access RT-PCR System
System for performing reverse transcription and PCR in a single buffer system.
T4 DNA Ligase Reaction Buffer
Reaction buffer for T4 DNA Ligase - 5 ml.
Library Efficiency DH5α Chemically Competent Cells
Chemically competent cells for transformation.
T4 Polynucleotide Kinase Reaction Buffer
Reaction buffer for T4 Polynucleotide Kinase - 4 ml.
Phusion® High-Fidelity PCR Kit
Phusion High-Fidelity PCR Kit - 200 reactions.
ImProm-II(TM) Reverse Transcriptase
Reverse transcriptase enzyme optimized for sensitive RT-PCR applications.
Bio-Rad Catalog Items
Discount pricing on most items from the Bio-Rad catalog with free shipping.
Analytical Method Development
MassBiologics provides analytical method development and optimization services as part of a larger program or as a stand-alone service, ranging from early discovery to robust methods transferred to Quality Control for cGMP activities.
Qiagen Catalog Items
Discount pricing on items from the Qiagen catalog with free shipping.
NEBNext Quick Ligation Reaction Buffer (5X)
NEBNext Quick Ligation Reaction Buffer (5X) - 2 ml.
Taq DNA Ligase Reaction Buffer
Reaction buffer for Taq DNA Ligase - 6 ml.
Q5® Reaction Buffer Pack
Q5 Reaction Buffer Pack - 6 ml.
StickTogether™ DNA Ligase Buffer
StickTogether DNA Ligase Buffer - 2 ml.
Xcellerex XDR 10 single-use stirred-tank bioreactor
The single-use Xcellerex XDR 10 is a flexible, stirred-tank bioreactor system suitable for use in process development, small-scale production, and process troubleshooting.
Alkaline Protease Solution
Enzyme solution for protein digestion and sample processing.
Nuclease-free Water
Nuclease-free Water - 100 ml.
Exonuclease I Reaction Buffer
Reaction buffer for Exonuclease I - 6 ml.
ThermoPol® Reaction Buffer Pack
ThermoPol Reaction Buffer Pack - 6 ml.
PureYield(TM) Plasmid Miniprep System
System for rapid purification of plasmid DNA from E. coli.
AccessQuick(TM) RT-PCR System
Master mix system for fast reverse transcription and PCR amplification.
Wave 50 Bioreactor System
The WAVE Bioreactor system features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures.
Cell Lysis Buffer (CLD)
Buffer for cell lysis applications.
Magnesium Chloride (MgCl2) Solution
Magnesium Chloride (MgCl2) Solution - 6 ml.
Recombinant Albumin, Molecular Biology Grade
Recombinant Albumin, Molecular Biology Grade - 12 mg.
Resin
Purification resin for molecular biology applications.
LunaScript® Multiplex One-Step RT-PCR Kit
LunaScript Multiplex One-Step RT-PCR Kit - 250 reactions.
Elution Buffer
Buffer solution for eluting purified nucleic acids.
Antarctic Phosphatase Reaction Buffer
Reaction buffer for Antarctic Phosphatase - 6 ml.
4/40 Wash Solution
Wash solution component for specialized purification protocols.
Millipore Sigma Catalog Items
Discount pricing on many items from the Millipore Sigma catalog with free shipping.
Neutralization Solution (NSB)
Buffer solution for nucleic acid purification workflows.
Magnesium Chloride Solution, 25mM
Magnesium chloride solution for PCR and enzymatic optimization.
AKTA Pure
ÄKTA pure protein purification system is a flexible and intuitive chromatography system designed to meet purification challenges in research applications.
ÄKTA pilot 600 chromatography system
ÄKTA pilot 600 is a compact bench-top chromatography system with a wide flow and pressure range. It suits both production of technical batches and scale-up studies as well as small-scale production of GMP-grade material.
Column Wash Solution (CWA)
Wash solution component for purification columns.
Magnesium Sulfate (MgSO4) Solution
Magnesium Sulfate (MgSO4) Solution - 6 ml.
Maxwell(R) HT 96 gDNA Blood
High-throughput system for genomic DNA extraction from blood samples.
AKTA Avant
ÄKTA avant is a preparative protein purification chromatography system designed for fast and secure development of scalable methods and processes.
Blue Protein Loading Dye
Blue Protein Loading Dye - 8 ml.
Corning Tissue Culture Products, Buffers, and FBS
Tissue culture products, buffers, and fetal bovine serum with discount pricing and free shipping.
Tetanus Toxoid for Research
Tetanus Toxoid designated for research use (not for use in humans).
National Diagnostics Catalog Items
List pricing on items from the National Diagnostics catalog with free shipping.
Services
Development and validation of analytical assays to support characterization, release testing, and stability programs.
Cell line development and optimization for expression of biologic therapeutics to support process scale-up.
Preformulation and formulation development to improve product stability and manufacturability.
Design and optimization of downstream purification and concentration processes to produce clinical- and commercial-grade drug substance.
cGMP upstream and downstream production of bulk drug substance from cell culture systems for IND and commercial programs.
Creation and management of master and working cell banks under GMP to support consistent manufacturing.
Aseptic filling services for clinical and commercial vials and containers, accommodating small- to large-scale fills.
Quality control testing and release testing for investigational and commercial biologics.
Formal stability testing programs to assess product shelf life and support regulatory submissions.
Quality assurance functions and support systems for compliance with cGMP operations.
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Development and validation of analytical assays to support characterization, release testing, and stability programs.
Cell line development and optimization for expression of biologic therapeutics to support process scale-up.
Preformulation and formulation development to improve product stability and manufacturability.
Design and optimization of downstream purification and concentration processes to produce clinical- and commercial-grade drug substance.
cGMP upstream and downstream production of bulk drug substance from cell culture systems for IND and commercial programs.
Creation and management of master and working cell banks under GMP to support consistent manufacturing.
Aseptic filling services for clinical and commercial vials and containers, accommodating small- to large-scale fills.
Quality control testing and release testing for investigational and commercial biologics.
Formal stability testing programs to assess product shelf life and support regulatory submissions.
Quality assurance functions and support systems for compliance with cGMP operations.
Expertise Areas
- Clinical trial supply and early-phase clinical support
- Biologics process development
- cGMP biologics manufacturing
- Monoclonal antibody and nanobody discovery
- Analytical method development and stability testing
- Quality systems and regulatory compliance
- Technology transfer and project management
- Licensing and partner development
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Key Technologies
- Monoclonal antibody production
- Nanobody and secretory IgA therapeutics
- Mammalian cell culture
- Bacterial expression systems
- Downstream processing and purification
- Tangential flow filtration (TFF)
- Master and working cell banking
- Aseptic fill–finish and automated filling lines
- Analytical assay development and characterization
- Stability testing
- Preclinical animal models