Marius Pharmaceuticals
Marius Pharmaceuticals is dedicated to revolutionizing hormone health and metabolic vitality through science-backed therapies, focusing on addressing testosterone deficiency in men and women. Their mission is to improve lives by providing innovative, safe, and effective treatments, including the proprietary oral testosterone therapy KYZATREX. They aim to lead in research, education, and patient care in the field of hormone and metabolic health.
Industries
Nr. of Employees
small (1-50)
Marius Pharmaceuticals
2301 Sugar Bush Rd # 510, Raleigh, NC 27612
Patents
Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-12295961-B2
View DetailsModulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-11590146-B2
View DetailsModulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-10576090-B2
View DetailsModulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-10576089-B2
View Details
Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-12295961-B2
View DetailsModulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-11590146-B2
View DetailsModulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-10576090-B2
View DetailsModulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols
US-10576089-B2
View DetailsProducts
Oral testosterone undecanoate softgel formulation
An oral softgel testosterone undecanoate formulation designed for lymphatic absorption to provide systemic testosterone replacement while reducing first-pass hepatic exposure.
Oral testosterone undecanoate softgel formulation
An oral softgel testosterone undecanoate formulation designed for lymphatic absorption to provide systemic testosterone replacement while reducing first-pass hepatic exposure.
Services
Collaborative design and sponsorship of multi-center clinical trials, investigator-led pilot studies, and PK/safety studies with academic and clinical investigators.
Establish and manage partnerships with clinic networks, telehealth and digital wellness providers, and health systems to expand product availability and support patient access programs.
Design and operationalize global early access and compassionate use programs via third-party service partners to provide therapy access prior to or shortly after approval.
Develop and run disease awareness campaigns and digital educational resources to inform patients and clinicians about diagnosis, treatment options, and monitoring requirements.
Advisory support for regulatory filings, labeling discussions, and patent/IP management, including preparation for regulatory listings and support for market entry.
Coordinate partnerships with academic medical centers to support design and conduct of translational and interventional research programs in perioperative and critical care settings.
Collaborative design and sponsorship of multi-center clinical trials, investigator-led pilot studies, and PK/safety studies with academic and clinical investigators.
Establish and manage partnerships with clinic networks, telehealth and digital wellness providers, and health systems to expand product availability and support patient access programs.
Design and operationalize global early access and compassionate use programs via third-party service partners to provide therapy access prior to or shortly after approval.
Develop and run disease awareness campaigns and digital educational resources to inform patients and clinicians about diagnosis, treatment options, and monitoring requirements.
Advisory support for regulatory filings, labeling discussions, and patent/IP management, including preparation for regulatory listings and support for market entry.
Coordinate partnerships with academic medical centers to support design and conduct of translational and interventional research programs in perioperative and critical care settings.
Expertise Areas
- Testosterone replacement therapy development
- Clinical trial management and execution
- Formulation development for lymphatic-mediated oral delivery
- Regulatory affairs and submissions
Key Technologies
- Lymphatic-mediated oral delivery
- Softgel capsule formulation
- Lipid/phytosterol-based excipient systems for oral bioavailability
- Ambulatory blood pressure monitoring (ABPM)
News & Updates
Marius Announces Ambulatory Blood Pressure Results Published in the Journal of Clinical Hypertension
A study showing minimal increases in ambulatory blood pressure following 120 days on KYZATREX, with no clinical significance in normotensive men.
Partnership to expand access to KYZATREX through affiliated urologic in-office dispensaries.
An awareness initiative to educate men about testosterone deficiency and treatment options.
The company received its sixth U.S. patent for KYZATREX, extending coverage to 2040.
Sponsoring the event focused on XY Chromosome Variations, including Klinefelter’s Syndrome, highlighting KYZATREX as a treatment option.
Launching a new website and introducing the Longevity and Endocrinology Advisory Boards with leading experts.
Marius Announces Ambulatory Blood Pressure Results Published in the Journal of Clinical Hypertension
A study showing minimal increases in ambulatory blood pressure following 120 days on KYZATREX, with no clinical significance in normotensive men.
Partnership to expand access to KYZATREX through affiliated urologic in-office dispensaries.
An awareness initiative to educate men about testosterone deficiency and treatment options.
The company received its sixth U.S. patent for KYZATREX, extending coverage to 2040.
Sponsoring the event focused on XY Chromosome Variations, including Klinefelter’s Syndrome, highlighting KYZATREX as a treatment option.
Launching a new website and introducing the Longevity and Endocrinology Advisory Boards with leading experts.