MalarVx, Inc.


MalarVx, Inc. is a Seattle-based biopharmaceutical company dedicated to developing effective malaria vaccines. Founded in 2012, the company aims to eradicate malaria through innovative technologies, including RNA-based vaccines and in vitro culture systems for the malaria parasite. They focus on creating safe, effective, and long-lasting vaccines to combat malaria globally, addressing the significant health burden caused by _Plasmodium_ parasites, especially in endemic regions like sub-Saharan Africa.

Industries

biotechnology
health-care
pharmaceutical

Nr. of Employees

small (1-50)

MalarVx, Inc.

Seattle, Washington, United States, North America


Products

Replicon RNA-based CSP malaria vaccine candidate

A clinical-stage malaria vaccine candidate using self-amplifying replicon RNA encoding circumsporozoite protein antigens formulated with lipid nanoparticle-style delivery for induction of immune responses against Plasmodium falciparum.

In vitro-cultured sporozoite whole-organism vaccine project

Research and development project focused on producing attenuated or whole-organism malaria vaccine materials via in vitro culture of mosquito-stage parasites to reduce dependence on mosquito-derived sporozoites.


Services

Collaborative research and development partnerships

Partnered R&D collaborations with academic labs, research institutes, and industry partners for vaccine formulation, immunology analysis, and parasite culture.

Expertise Areas

  • Clinical-stage vaccine development
  • Malaria parasite biology and in vitro culture
  • Vaccine formulation and nucleic acid delivery
  • Whole-organism vaccine production
  • Show More (4)

Key Technologies

  • Self-amplifying replicon RNA (replicon RNA) platforms
  • Lipid nanoparticle-style vaccine delivery
  • In vitro sporozoite and mosquito-stage culture systems
  • Whole-organism vaccine production methods
  • Show More (3)

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