MabPlex International


MabPlex International is a leading global biopharmaceutical CDMO service provider, specializing in antibody, linker-toxin, and ADC production. With innovative technology, rich experience, and a professional team, MabPlex helps clients accelerate drug development from research to commercialization, contributing to the development of China's biopharmaceutical industry and promoting human health. The company has established R&D and production bases in China and the USA, and is recognized as a high-tech enterprise and a public service platform for antibody drug R&D and industrialization in Shandong.

Industries

association
biotechnology
manufacturing
non-profit

Nr. of Employees

large (251-1000)

MabPlex International

No. 60 Beijing Middle Road, Yantai Free Trade Zone, Shandong, China


Patents

Method for producing antibody-drug conjugate intermediate by addition of acid and use thereof

US-11833219-B2

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One-pot process for preparing intermediate of antibody-drug conjugate

US-11717575-B2

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Antibody-drug conjugates and uses thereof

US-11596693-B2

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Products

CHO serum‑free production medium (basal and feed variants)

Serum‑free media formulations for suspension CHO cell lines, provided as basal and feed variants to support cell line development, high‑density culture and high recombinant protein/antibody expression.

Linker–payload library and custom linker/payload supply

On‑hand linker–payload variants and custom synthesis services for ADC development, supplying material from milligram to multi‑gram scale to support screening and early development needs.


Services

End‑to‑end services including early discovery/CMC research, cell line development, process and analytical development, clinical sample manufacturing, regulatory filing support and commercial GMP production.

Provision of an on‑hand library of linker–payload variants for rapid ADC screening, custom design and synthetic supply from milligram through multi‑gram scale to support conjugation and early development.

Newly commissioned pre‑filled syringe production line with released clinical samples and capabilities to support PFS manufacturing alongside vial and lyophilized product formats.

On‑site analytical laboratory services covering in‑process controls, release assays, stability study design and execution (long‑term, accelerated, forced degradation) to support product release and regulatory submissions.

Consulting for CMC regulatory strategy, CTD Module 3 drafting and submission support (IND/CTA/IMPD, BLA/MAA), including meeting preparation and correspondence with regulatory authorities.

Implementation of Warehouse Management Systems with IoT integration and deployment/PQ of electronic document and training management systems to enable validated digital quality and material workflows.

Expertise Areas

  • Biologics GMP manufacturing and commercialization
  • Antibody–drug conjugate (ADC) development and manufacturing
  • Cell line development and high‑titer expression platforms
  • Upstream and downstream process development and scale‑up
  • Show More (6)

Key Technologies

  • Suspension CHO cell culture
  • Scale‑up to 2000 L bioreactors
  • High‑throughput clone screening and Ambr/mini‑bioreactor systems
  • Automated multi‑mode chromatography
  • Show More (6)

News & Updates

MabPlex was awarded the 2024 Yantai Biopharmaceutical Innovation Star Enterprise.

MabPlex's warehouse management system (WMS) has been successfully launched, enhancing supply chain management.

MabPlex held its 2024 annual summary and 2025 work deployment conference.

MabPlex was honored as a leading enterprise in biopharmaceutical innovation in Yantai for 2024.

The new WMS system improves MabPlex's supply chain efficiency and compliance.

MabPlex held its 2024 annual summary and 2025 work deployment conference.

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