Lumen Bioscience


Developer of a spirulina-based platform for expressing and delivering therapeutic proteins. The company engineers Arthrospira (spirulina) to produce high-yield biologics intended for oral or topical delivery, and operates integrated discovery, development, GMP manufacturing, and clinical operations to advance candidates from preclinical work through clinical trials.

Industries

Biopharma
Biotechnology
Health Care
Life Science
Pharmaceutical
Biotechnology Research

Nr. of Employees

medium (51-250)

Lumen Bioscience

Seattle, Washington, United States


Patents

Arthrospira platensis non-parenteral therapeutic delivery platform

US-12503682-B2

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Leptin compositions and methods of making and using the same to support weight loss and/or maintenance

US-12466883-B1

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Arthrospira platensis oral vaccine delivery platform

US-12447202-B2

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Thermostable phycobiliproteins produced from recombinant arthrospira

US-12252513-B2

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Targeted mutagenesis in spirulina

US-12065638-B2

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Cyanobacteria having improved photosynthetic activity

US-11279912-B2

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Products

Orally delivered biologic cocktail for C. difficile (LMN-201)

Oral biologic cocktail designed to treat C. difficile colitis; listed in Phase 2/3 clinical stage on company pipeline.

Oral biologic cocktail for inflammatory bowel disease (IBD)

Spirulina-derived biologic cocktail intended for Crohn’s disease and ulcerative colitis; described as preclinical with rationale for oral, low-cost delivery.

Antibody cocktail for gastroenteritis (field POC 2026)

Antibody cocktail designed to neutralize common GI pathogens; early ileostomy PK and field studies reported, with a proof-of-concept study planned.

Intranasal biologic for viral respiratory infections

Intranasal biologic intended to support nasal barrier function and reduce viral attachment and transmission; reported to be in Phase 1 development.

Intranasal vaccine candidate for malaria

Exploratory/preclinical intranasal vaccine program targeting Plasmodium infection; intended as a low-cost, stable adjunct for endemic regions.

Spirulina-derived protein ingredient (LMN-0801)

Research-stage, spirulina-derived protein ingredient produced by the oral protein platform; described as ongoing research.

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Expertise Areas

  • Oral biologics development
  • Microalgal biomanufacturing
  • Protein engineering and antibody discovery
  • GMP biologics production and downstream processing
  • Show More (4)

Key Technologies

  • Microalgal expression systems (spirulina)
  • CRISPRi and genetic engineering
  • Phage panning/display
  • Photobioreactors and large-scale cultivation
  • Show More (6)

News & Updates

Company-published report of preliminary cohort results showing clinical cures for C. difficile infection.

Article covering defense funding and potential cost-reduction implications for antibody manufacturing using the company's platform.

Announcement of a $30M Series C extension to support platform and pipeline development.


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