Lightcast Discovery


Lightcast is a biotechnology company focused on developing a flexible platform for single-cell functional analysis. Their mission is to enable precise interrogation of single cell heterogeneity, interactions, and functional behaviors to accelerate discovery across various disciplines, including basic research, translational research, and drug discovery. They aim to support the development of therapeutics and improve understanding of cellular communication and behavior.

Industries

Biotechnology
Health Care
Medical
Biotechnology Research

Nr. of Employees

medium (51-250)

Lightcast Discovery


Patents

Droplet manipulation device and method

US-12350670-B2

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Device and method for microdroplet detection of cells

US-12157123-B2

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Microdroplet manipulation method

US-12134098-B2

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Microfluidic analytical device

US-12030055-B2

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Microdroplet manipulation device

US-12017224-B2

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Single nucleotide detection method and associated probes

US-11920192-B2

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Products

Single-cell functional analysis platform

A platform combining droplet microfluidics and associated hardware/software to perform massively parallel single-cell functional assays with controlled droplet merging, sequential assay capability, and live cell dispensing compatible with standard well plates for downstream use.

Envisia

A fully integrated single-cell screening platform combining advanced instrumentation, intelligent software, and purpose-built cartridges utilizing optical electrowetting-on-dielectric (oEWOD) droplet technology.


Services

Programmatic early access for selected users to evaluate and pilot the single-cell functional analysis platform and workflows.

Provision of peer-reviewed publications, white papers and technical resources describing platform technology, methods and application case studies.

Expertise Areas

  • Single-cell functional analysis
  • Biomolecule secretion profiling
  • Cell–cell interaction assays
  • Cytotoxicity and targeted cell-killing assays
  • Show More (5)

Key Technologies

  • Droplet microfluidics
  • Controlled droplet merging
  • Sequential droplet merging workflows
  • Electrowetting-on-dielectric (EWOD) integrated microfluidics
  • Show More (6)

News & Updates

Lightcast announced the appointment of Philip Binns as Chairman of the Board on June 2, 2025.

On May 10, 2025, Lightcast announced the limited commercial release of Envisia, a platform for single-cell functional analysis aimed at antibody discovery.

An article published on May 12, 2025, discussing overlooked aspects of traditional workflows in the context of single-cell analysis.

A scientific paper published by Lightcast, details not specified in the provided content.

On May 30, 2025, Lightcast announced securing $49 million in Series B funding to support commercialization.


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