Karius
Karius is revolutionizing infectious disease diagnostics by leveraging clinical metagenomics, genomics, and AI to provide rapid, accurate, and broad detection of pathogens. Their mission is to create a world where every patient gets a clear and timely diagnosis, especially focusing on life-threatening infections in immunocompromised patients. They develop innovative laboratory tests, including the Karius SpectrumTM, a minimally invasive blood test that detects over 1,000 fungi, bacteria, and DNA viruses, aiding in the diagnosis and management of infections. The company is committed to high ethical standards, scientific excellence, and improving patient outcomes through advanced genomic diagnostics.
Industries
Nr. of Employees
medium (51-250)
Karius
Redwood City, California, United States, North America
Products
Plasma metagenomic pathogen detection test
A laboratory-developed plasma metagenomic sequencing test that detects and quantifies microbial cell-free DNA from bacteria, fungi, parasites, and DNA viruses to aid diagnosis of systemic and deep-seated infections.
Metagenomic lung specimen diagnostic (BAL-focused)
Metagenomic sequencing workflow tailored for bronchoalveolar lavage (BAL) and pulmonary infection diagnostic contexts to assist in diagnosis and management of lung infections, particularly in immunocompromised patients.
Plasma metagenomic pathogen detection test
A laboratory-developed plasma metagenomic sequencing test that detects and quantifies microbial cell-free DNA from bacteria, fungi, parasites, and DNA viruses to aid diagnosis of systemic and deep-seated infections.
Metagenomic lung specimen diagnostic (BAL-focused)
Metagenomic sequencing workflow tailored for bronchoalveolar lavage (BAL) and pulmonary infection diagnostic contexts to assist in diagnosis and management of lung infections, particularly in immunocompromised patients.
Services
Send-out plasma metagenomic testing service
Clinical laboratory service performing plasma-based metagenomic sequencing for broad pathogen detection from a single blood draw, including quantitative reporting and optional genotypic AMR marker detection.
Clinical and biopharma study collaboration and diagnostic partnership services
Collaborative engagements to integrate metagenomic pathogen testing into clinical trials, multicenter observational studies, and real-world evidence programs; includes operational support for sample collection, data integration, and study diagnostic endpoints.
Send-out plasma metagenomic testing service
Clinical laboratory service performing plasma-based metagenomic sequencing for broad pathogen detection from a single blood draw, including quantitative reporting and optional genotypic AMR marker detection.
Clinical and biopharma study collaboration and diagnostic partnership services
Collaborative engagements to integrate metagenomic pathogen testing into clinical trials, multicenter observational studies, and real-world evidence programs; includes operational support for sample collection, data integration, and study diagnostic endpoints.
Expertise Areas
- Clinical metagenomics for infectious disease
- Infectious disease diagnostic testing using plasma microbial cell-free DNA
- Clinical trial and multicenter observational study design and execution
- Diagnostic stewardship and clinical result interpretation
Key Technologies
- Metagenomic next-generation sequencing (mNGS)
- Microbial cell-free DNA (mcfDNA) analysis
- Direct-to-library sequencing library preparation
- Machine learning / AI for genomic interpretation