Itr Laboratories Canada
ITR Laboratories Canada is a global contract research organization (CRO) located in Montreal, Quebec, with over 30 years of experience. The company specializes in efficacy, toxicology, and laboratory services for molecules, aiming to develop new medicines that alleviate patient suffering and improve human health. They are committed to ethical animal research, regulatory compliance, and advancing medical progress through innovative preclinical research programs conducted in state-of-the-art facilities.
Industries
Nr. of Employees
large (251-1000)
Services
Preclinical toxicology studies
GLP-compliant nonclinical safety studies across dose ranges and durations (single dose to carcinogenicity) with clinical observations, clinical pathology and study reporting.
Inhalation toxicology and aerosol testing
Preclinical inhalation study design, aerosol characterization for dry powder, metered dose and nebulized products, and operation of inhalation exposure systems for pulmonary delivery assessment.
Analytical and bioanalytical services
Dose formulation analysis and biological sample quantitation using HPLC/UHPLC, GC, LC‑MS/MS with validated sample extraction workflows to support PK/TK, biodistribution and toxicology studies.
Biomarker and immunology assay services
Execution and validation of immunoassays and biomarker assays, including ELISA/ECL, immunophenotyping, TDAR, NK assays, receptor occupancy and multiplex cytokine assays to support pharmacodynamics and safety endpoints.
GLP method development, validation and reporting
Method development and GLP validation/qualification of analytical and biomarker assays, QA oversight and preparation of GLP‑compliant study documentation and reports.
Animal husbandry, veterinary support and enrichment programs
Comprehensive animal care including veterinary medical care, enrichment programs, and institutional oversight to maintain welfare standards and support study integrity.
Preclinical toxicology studies
GLP-compliant nonclinical safety studies across dose ranges and durations (single dose to carcinogenicity) with clinical observations, clinical pathology and study reporting.
Inhalation toxicology and aerosol testing
Preclinical inhalation study design, aerosol characterization for dry powder, metered dose and nebulized products, and operation of inhalation exposure systems for pulmonary delivery assessment.
Analytical and bioanalytical services
Dose formulation analysis and biological sample quantitation using HPLC/UHPLC, GC, LC‑MS/MS with validated sample extraction workflows to support PK/TK, biodistribution and toxicology studies.
Biomarker and immunology assay services
Execution and validation of immunoassays and biomarker assays, including ELISA/ECL, immunophenotyping, TDAR, NK assays, receptor occupancy and multiplex cytokine assays to support pharmacodynamics and safety endpoints.
GLP method development, validation and reporting
Method development and GLP validation/qualification of analytical and biomarker assays, QA oversight and preparation of GLP‑compliant study documentation and reports.
Animal husbandry, veterinary support and enrichment programs
Comprehensive animal care including veterinary medical care, enrichment programs, and institutional oversight to maintain welfare standards and support study integrity.
Expertise Areas
- Preclinical toxicology study management
- Inhalation toxicology and aerosol sciences
- Bioanalysis and PK/TK quantitation
- Immunology and biomarker assay development
Key Technologies
- High‑performance liquid chromatography (HPLC/UHPLC)
- Gas chromatography (GC/GC‑MS)
- Liquid chromatography–tandem mass spectrometry (LC‑MS/MS)
- 96‑well plate bioanalytical workflows