Itr Laboratories Canada
ITR Laboratories Canada is a global contract research organization (CRO) located in Montreal, Quebec, with over 30 years of experience. The company specializes in efficacy, toxicology, and laboratory services for molecules, aiming to develop new medicines that alleviate patient suffering and improve human health. They are committed to ethical animal research, regulatory compliance, and advancing medical progress through innovative preclinical research programs conducted in state-of-the-art facilities.
Industries
Nr. of Employees
large (251-1000)
Services
GLP-compliant nonclinical safety studies across dose ranges and durations (single dose to carcinogenicity) with clinical observations, clinical pathology and study reporting.
Preclinical inhalation study design, aerosol characterization for dry powder, metered dose and nebulized products, and operation of inhalation exposure systems for pulmonary delivery assessment.
Dose formulation analysis and biological sample quantitation using HPLC/UHPLC, GC, LC‑MS/MS with validated sample extraction workflows to support PK/TK, biodistribution and toxicology studies.
Execution and validation of immunoassays and biomarker assays, including ELISA/ECL, immunophenotyping, TDAR, NK assays, receptor occupancy and multiplex cytokine assays to support pharmacodynamics and safety endpoints.
Method development and GLP validation/qualification of analytical and biomarker assays, QA oversight and preparation of GLP‑compliant study documentation and reports.
Comprehensive animal care including veterinary medical care, enrichment programs, and institutional oversight to maintain welfare standards and support study integrity.
GLP-compliant nonclinical safety studies across dose ranges and durations (single dose to carcinogenicity) with clinical observations, clinical pathology and study reporting.
Preclinical inhalation study design, aerosol characterization for dry powder, metered dose and nebulized products, and operation of inhalation exposure systems for pulmonary delivery assessment.
Dose formulation analysis and biological sample quantitation using HPLC/UHPLC, GC, LC‑MS/MS with validated sample extraction workflows to support PK/TK, biodistribution and toxicology studies.
Execution and validation of immunoassays and biomarker assays, including ELISA/ECL, immunophenotyping, TDAR, NK assays, receptor occupancy and multiplex cytokine assays to support pharmacodynamics and safety endpoints.
Method development and GLP validation/qualification of analytical and biomarker assays, QA oversight and preparation of GLP‑compliant study documentation and reports.
Comprehensive animal care including veterinary medical care, enrichment programs, and institutional oversight to maintain welfare standards and support study integrity.
Expertise Areas
- Preclinical toxicology study management
- Inhalation toxicology and aerosol sciences
- Bioanalysis and PK/TK quantitation
- Immunology and biomarker assay development
Key Technologies
- High‑performance liquid chromatography (HPLC/UHPLC)
- Gas chromatography (GC/GC‑MS)
- Liquid chromatography–tandem mass spectrometry (LC‑MS/MS)
- 96‑well plate bioanalytical workflows
News & Updates
A successful toxicology study at ITR has supported Bright Minds Biosciences' treatment for Dravet Syndrome moving into clinical trials.
Accreditation and Inspection
ITR Laboratories Canada is accredited by CCAC, AAALAC, FDA, and EMA, ensuring high standards of animal welfare and regulatory compliance.
Support for Inhalation Technologies
Extensive experience in aerosol sciences, inhalation toxicology, and lung pathology, supporting over 500 inhalation toxicology studies.
A successful toxicology study at ITR has supported Bright Minds Biosciences' treatment for Dravet Syndrome moving into clinical trials.
Accreditation and Inspection
ITR Laboratories Canada is accredited by CCAC, AAALAC, FDA, and EMA, ensuring high standards of animal welfare and regulatory compliance.
Support for Inhalation Technologies
Extensive experience in aerosol sciences, inhalation toxicology, and lung pathology, supporting over 500 inhalation toxicology studies.