Invitrolize
Invitrolize is a company dedicated to early detection of harmful respiratory compounds through innovative in vitro models, notably ALIsens®, which can identify respiratory sensitizers and irritants under realistic exposure conditions. The company emphasizes quality, regulatory acceptance, and animal-free testing, with a strong focus on scientific validation and international standards. It has received multiple awards for its technology, including the Lush Prize and recognition from PETA and ESTIV, and is actively involved in advancing in vitro respiratory toxicity testing methods.
Industries
Nr. of Employees
small (1-50)
Invitrolize
Products
Alveolar in vitro model for inhalation hazard assessment
A patented, award-recognized in vitro alveolar barrier model cultured at the air-liquid interface designed to identify respiratory sensitizers and differentiate them from respiratory irritants using marker expression, cytokines and gene expression endpoints.
Alveolar in vitro model for inhalation hazard assessment
A patented, award-recognized in vitro alveolar barrier model cultured at the air-liquid interface designed to identify respiratory sensitizers and differentiate them from respiratory irritants using marker expression, cytokines and gene expression endpoints.
Services
Laboratory testing service using a 3D alveolar co-/tetra-culture at the air-liquid interface to assess potential respiratory sensitizers and irritants, reporting marker expression, cytokines and viability endpoints.
Laboratory testing service using a 3D alveolar co-/tetra-culture at the air-liquid interface to assess potential respiratory sensitizers and irritants, reporting marker expression, cytokines and viability endpoints.
Expertise Areas
- In vitro respiratory toxicology
- Air-liquid interface exposure models
- Respiratory sensitization and irritation hazard assessment
- Nanomaterial and aerosol inhalation testing
Key Technologies
- Air-liquid interface (ALI) exposure
- 3D alveolar coculture/tetraculture models
- Aerosol and nanoparticle generation and dose-controlled exposure
- Cell-surface marker assays (TSLPr, CD54, CD86)