Intersouth Partners
Intersouth Partners is a venture capital firm based in Durham, North Carolina, with a history dating back to 1985. It manages $780 million across seven funds, making it the largest venture capital fund in North Carolina and one of the largest in the Southeast. The firm invests in technology and life science sectors, leveraging extensive industry expertise and a broad network to support early-stage companies. Intersouth has invested in over 100 private companies, fostering innovation and entrepreneurship in the region. Currently, it is not making new investments.
Industries
Nr. of Employees
small (1-50)
Intersouth Partners
Durham, North Carolina, United States, North America
Services
Venture capital investment (seed to growth)
Providing capital to early‑stage and growth companies across technology and life science sectors, including leading and co‑leading financing rounds.
Board, governance and interim executive advisory
Board membership, governance guidance and temporary executive leadership to support operational transitions and growth.
Company incubation and mentoring
Seed funding, office incubation and mentoring for scientific founders and early teams to develop business plans, licensing and initial commercialization.
Strategic exits and transaction advisory
Advisory and execution support for mergers, acquisitions, public offerings and similar exit transactions, including negotiating and coordinating deal execution.
Clinical development advisory for therapeutics
Support for therapeutic companies advancing programs through discovery and clinical trial phases, including helping assemble financing and strategic partners for development.
Venture capital investment (seed to growth)
Providing capital to early‑stage and growth companies across technology and life science sectors, including leading and co‑leading financing rounds.
Board, governance and interim executive advisory
Board membership, governance guidance and temporary executive leadership to support operational transitions and growth.
Company incubation and mentoring
Seed funding, office incubation and mentoring for scientific founders and early teams to develop business plans, licensing and initial commercialization.
Strategic exits and transaction advisory
Advisory and execution support for mergers, acquisitions, public offerings and similar exit transactions, including negotiating and coordinating deal execution.
Clinical development advisory for therapeutics
Support for therapeutic companies advancing programs through discovery and clinical trial phases, including helping assemble financing and strategic partners for development.
Expertise Areas
- Venture capital and fund management
- Early‑stage investing and seed financing
- Portfolio company governance and board leadership
- Technology assessment and commercialization
Key Technologies
- Monoclonal antibody therapeutics
- Genomics and DNA sequencing
- Bioinformatics
- Drug discovery and preclinical development