Humanigen


Humanigen is a biopharmaceutical company dedicated to developing innovative therapies. Their mission is to create effective treatments to improve patient outcomes. They focus on research and development in the biotech sector.

Industries

biopharma
biotechnology
health-care
pharmaceutical

Nr. of Employees

small (1-50)

Humanigen

Burlingame, California, United States, North America


Patents

Method of increasing the efficacy of CAR-T immunotherapy using lenzilumab

US-11673962-B2

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Methods of treating CART-T cell therapy-induced neuroinflammation using a GM-CSF antagonist

US-11130805-B2

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Method of reducing tumor relapse rate in immunotherapy by administration of lenzilumab

US-10927168-B2

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Immunoglobulin variable region cassette exchange

US-10919983-B2

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Method of reducing the level of non-GM-CSF cytokines/chemokines in immunotherapy-related toxicity

US-10899831-B2

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Methods of treating immunotherapy-related toxicity using a GM-CSF antagonist

US-10870703-B2

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Products

Clinical-stage monoclonal antibody targeting GM-CSF

A human monoclonal antibody candidate designed to neutralize granulocyte–macrophage colony-stimulating factor (GM-CSF) to reduce cytokine-driven inflammation and related clinical complications; advanced through preclinical studies and clinical trials for acute respiratory and immunotherapy-associated cytokine release conditions.


Services

Sponsor-led clinical development services covering protocol design, trial execution, clinical operations, and data analysis for clinical-stage biologics.

Expertise Areas

  • Clinical trial management
  • Monoclonal antibody therapeutics
  • Cytokine biology and GM-CSF modulation
  • Translational biomarker development
  • Show More (5)

Key Technologies

  • Monoclonal antibody platforms
  • Cytokine and multiplex immunoassays
  • Flow cytometry
  • Preclinical in vivo disease models
  • Show More (3)

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