Hope Biosciences LLC


Hope Biosciences is a biopharmaceutical company dedicated to developing and delivering adult stem cell solutions that are safe, effective, and affordable for incurable conditions. They focus on regenerative medicine, stem cell culture, banking, and therapeutics, with a mission to redefine disease treatment and prevention through innovative cell-based therapies. The company emphasizes quality, safety, and proprietary technology, and collaborates with academic and clinical research organizations to bring high-volume, consistent, and repeatable mesenchymal stem cells to patients. They are actively involved in FDA-authorized clinical trials for conditions such as COVID-19, multiple sclerosis, Alzheimer’s, traumatic brain injury, and more, and have received significant funding including a nearly $5 million Department of Defense grant for TBI research.

Industries

biopharma
biotechnology
pharmaceutical

Nr. of Employees

small (1-50)

Hope Biosciences LLC


Patents

Culture media for multipotent stem cells

US-11111480-B2

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Formulation for storage, transportation, and delivery of protein rich conditioned medium

US-10988731-B2

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Method of banking stem cells

US-10959425-B2

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Method for generating protein rich conditioned medium

US-10894947-B1

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Container for storing biological material

US-D875967-S1

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Culture media for multipotent stem cells

US-10513689-B2

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Products

MSC-derived conditioned media (secretome)

Cell-culture-derived conditioned media containing proteins, cytokines, and growth factors collected from undifferentiated mesenchymal stem cell cultures for topical or research applications.

Topical serum formulated from conditioned media

Shelf-stable topical gel product formulated using MSC-conditioned media for topical skin applications.

Clinical-grade autologous MSC therapeutic doses

Individual therapeutic cell doses manufactured from a patient's own cultured mesenchymal stem cells for investigational use in clinical trials and expanded access, intended for intravenous administration.


Services

Service to collect adipose tissue, isolate and expand mesenchymal stem cells, and establish master and working cell banks with clinical-grade testing and cryostorage.

Processing and storage of placenta-derived tissue to isolate mesenchymal stem cells, create master cell banks, and store vials for potential future therapeutic manufacturing.

Manufacture of autologous mesenchymal stem cell therapeutic doses for use in clinical trials and expanded access, including multi-dose production, QC release, and shipment of fresh or cryopreserved doses to clinical sites.

Management of expanded access requests through structured intake, clinical review, medical record assessment, and prioritization to facilitate investigational therapy access.

Production of MSC-conditioned media and formulation into shelf-stable topical gel products for cosmetic or research applications.

Expertise Areas

  • Autologous mesenchymal stem cell manufacturing and scale-up
  • Clinical-grade stem cell banking for adults and newborns
  • Clinical trial management and execution (Phase I–II/IIb, randomized and non-randomized designs)
  • Regulatory submissions and FDA protocol compliance
  • Show More (6)

Key Technologies

  • Mesenchymal stem cell isolation and expansion
  • Master cell bank and working cell bank generation
  • Custom cell culture media and reagent systems
  • Conditioned media / cell-secreted secretome processing
  • Show More (6)

News & Updates

Hope Biosciences announced positive results from a Phase II clinical trial showing the safety and potential efficacy of stem cell therapy for multiple sclerosis.

The company received FDA approval for a Phase II clinical trial evaluating stem cell therapy to support immunity against COVID-19.

Hope Biosciences partnered with Altoida, Inc. to evaluate stem cell therapy for Alzheimer’s, utilizing digital biomarkers for early detection and treatment.

Hope Biosciences announced positive results from a Phase II clinical trial showing the safety and potential efficacy of stem cell therapy for multiple sclerosis.

The company received FDA approval for a Phase II clinical trial evaluating stem cell therapy to support immunity against COVID-19.

Hope Biosciences partnered with Altoida, Inc. to evaluate stem cell therapy for Alzheimer’s, utilizing digital biomarkers for early detection and treatment.

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