Headache Sciences Incorporated


Clinical artificial-intelligence company developing an EEG-based diagnostic and monitoring service for migraine. The organization combines EEG signal processing, machine learning classifiers and source-localization visualization to identify interictal migraine biomarkers, has peer-reviewed publications and an awarded US patent for its diagnostic approach, and is running IRB-approved clinical studies to validate its algorithms and prototypes.

Industries

N/A

Nr. of Employees

small (1-50)


Patents

Diagnosis of migraine via expert system

US-10932725-B2

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Products

EEG-based migraine diagnostic prototype (SaMD)

Prototype diagnostic system using machine-learning analysis of EEG to identify interictal migraine predisposition and subtype (migraine with aura, migraine without aura).


Services

Recruitment and enrollment of participants, collection of standardized multi-lead EEG recordings, and data-generation for validation of diagnostic algorithms.

Provision of EEG recording according to defined multi-lead protocol (32 leads) to generate data compatible with machine-learning diagnostic algorithms.

Expertise Areas

  • EEG signal processing
  • Biomarker discovery and validation
  • Machine learning for clinical diagnostics
  • SaMD (software-as-a-medical-device) development
  • Show More (4)

Key Technologies

  • Electroencephalography (EEG)
  • Machine learning classification (non-linear SVM)
  • Biosignal signal processing
  • Source localization for EEG
  • Show More (3)

News & Updates

Clinical trials for biomarker validation commenced (September 3, 2022).

Received FDA correspondence (July 13, 2022) providing a roadmap for applying for breakthrough status for chronic migraine pending additional research.

Unconditional IRB ethics approval obtained to validate existing biomarkers and discover additional biomarkers (June 9, 2022).

Peer-reviewed proof-of-concept publication describing machine-learning methods applied to EEG for migraine with aura classification.

US patent awarded for an expert-system approach to diagnosing migraine using machine learning applied to EEG.

Pilot study achieving ~92.9% classification accuracy for migraine with aura (interictal) versus controls; additional preliminary 3-class results reported.

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