GRAIL, Inc.


GRAIL is a healthcare company dedicated to early cancer detection through innovative technologies like the Galleri® multi-cancer early detection test. Their mission is to detect cancer early, when it can be cured, and to transform cancer screening and care by harnessing genomics and machine learning. They collaborate with leading health systems and academic centers worldwide to bring their groundbreaking technology to patients.

Industries

biotechnology

Nr. of Employees

Very Large (1000+)

GRAIL, Inc.


Patents

Methods of preparing dual-indexed DNA libraries for bisulfite conversion sequencing

US-12264364-B2

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Using nucleic acid size range for noninvasive cancer detection

US-12247259-B2

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Detecting cross-contamination in sequencing data

US-12237053-B2

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Systems and methods for using a convolutional neural network to detect contamination

US-12236346-B2

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Source of origin deconvolution based on methylation fragments in cell-free DNA samples

US-12234514-B2

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Systems and methods for classifying patients with respect to multiple cancer classes

US-12191000-B2

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Products

Multi-cancer early detection blood test (MCED)

A blood-based screening assay that sequences circulating cell-free DNA and applies methylation-targeted analysis and machine learning to detect cancer signals and predict likely tissue-of-origin for positive results; intended to complement recommended single-cancer screening.

Diagnostic aid blood test for symptomatic patients (DAC)

A blood-based diagnostic aid intended to accelerate diagnostic resolution in patients presenting with non-specific signs and symptoms and a clinical suspicion of cancer by detecting cancer-associated methylation signals and suggesting likely cancer location.


Services

Competitive funding and collaboration program supporting investigator-sponsored trials and research collaborations, including LOI intake, protocol and budget review, contracting, and study start-up packages.

Provision of post-diagnosis, research-use-only blood-based liquid biopsy assays and collaborative programs for biopharma clinical research applications.

Services to streamline test ordering and result delivery by integrating test ordering into provider workflows and health IT platforms.

Expertise Areas

  • Multi-cancer early detection (MCED)
  • Cell-free DNA (cfDNA) analysis
  • Targeted methylation assay development
  • Machine learning for diagnostic classifiers
  • Show More (4)

Key Technologies

  • Targeted methylation sequencing
  • Cell-free DNA (cfDNA) sequencing
  • Next-generation sequencing
  • Machine learning classifiers
  • Show More (5)

News & Updates

GRAIL announced positive results from their PATHFINDER 2 study, a key milestone in their clinical development.

GRAIL announced inducement grants to new employees under NASDAQ rules.

GRAIL announced their participation in the Jefferies Healthcare Conference.

GRAIL released their financial results for Q1 2025.

GRAIL supports policy efforts to improve access to multi-cancer early detection.

GRAIL was recognized for its impact on society by Fortune magazine.

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