Genomics & Bioinformatics Core Facility
An institutional core facility that provides sequencing, single-cell and spatial transcriptomics, laboratory processing, and bioinformatics support to academic and industry researchers. The facility offers wet-lab services (library preparation, nucleic acid QC, fragmentation, size selection), access to high-throughput short-read sequencing and single-cell/spatial platforms, customized computational pipelines and high-performance computing access, plus consultation, training, and grant support.
Industries
N/A
Nr. of Employees
small (1-50)
Genomics & Bioinformatics Core Facility
Genomics & Bioinformatics Core Facility, B005 McCourtney Hall East, Notre Dame, IN 46556 USA
Services
End-to-end sample processing, library preparation, sequencing coordination, and initial data processing for single-cell and spatial gene-expression projects.
Library construction for DNA and RNA (including small RNA and amplicons), and sequencing using institutional short-read platforms and collaborative high-throughput options.
Nucleic acid quantification, integrity assessment, and fragment-size analysis to validate samples for sequencing and library workflows.
Development and execution of tailored analysis pipelines, visualization, and interpretation for genomics, transcriptomics, single-cell and spatial datasets; access to HPC and reproducible workflows.
Consultation on experimental design, budgeting, letters of support for grants, short-format computational training programs, and user guides/tutorials for facility systems.
End-to-end sample processing, library preparation, sequencing coordination, and initial data processing for single-cell and spatial gene-expression projects.
Library construction for DNA and RNA (including small RNA and amplicons), and sequencing using institutional short-read platforms and collaborative high-throughput options.
Nucleic acid quantification, integrity assessment, and fragment-size analysis to validate samples for sequencing and library workflows.
Development and execution of tailored analysis pipelines, visualization, and interpretation for genomics, transcriptomics, single-cell and spatial datasets; access to HPC and reproducible workflows.
Consultation on experimental design, budgeting, letters of support for grants, short-format computational training programs, and user guides/tutorials for facility systems.
Expertise Areas
- Genomics (short-read sequencing)
- Single-cell genomics
- Spatial transcriptomics
- Transcriptomics and RNA-Seq analysis
Key Technologies
- Next-generation sequencing (short-read)
- Single-cell RNA sequencing (scRNA-seq)
- Single-cell multiome (ATAC + gene expression)
- Spatial transcriptomics
News & Updates
Announcement of acquisition of microfluidic partitioning single-cell system to support single-cell and spatial genomics research.
Research using molecular and genomic markers to study hybrid zone movement and gene flow under climate change.
Announcement of acquisition of microfluidic partitioning single-cell system to support single-cell and spatial genomics research.
Research using molecular and genomic markers to study hybrid zone movement and gene flow under climate change.