Genetic Signatures Limited
Developer and commercialiser of a nucleic-acid simplification platform and associated multiplex real-time PCR workflows for infectious disease screening. Operates R&D, validation and production laboratories, produces sample processing reagents and assays, supports automated extraction/PCR workflows and distributes products via a global network. Holds a patent portfolio covering its nucleic‑acid simplification technology and has completed regulatory clearances for at least one diagnostic kit in the US.
Industries
Nr. of Employees
small (1-50)
Genetic Signatures Limited
Headquarters: Newtown, Sydney, Australia (company research & development and validation laboratories). Production facility: Maroubra, Sydney, Australia.
Patents
Methods for simplifying microbial nucleic acids by chemical modification of cytosines
US-8598088-B2
View DetailsIsothermal strand displacement amplification using primers containing a non-regular base
US-8431347-B2
View Details
Methods for simplifying microbial nucleic acids by chemical modification of cytosines
US-8598088-B2
View DetailsIsothermal strand displacement amplification using primers containing a non-regular base
US-8431347-B2
View DetailsProducts
Multiplex pathogen detection kits (multiplex real-time PCR)
Kits that enable simultaneous detection of multiple infectious pathogen targets using multiplexed real-time PCR workflows compatible with the company’s nucleic-acid simplification method.
Sample processing kits and conversion reagent
Sample processing kits that lyse specimens and isolate nucleic acids (DNA and RNA), and a bisulphite-based conversion reagent used to simplify nucleic-acid sequences prior to PCR.
Analyte specific reagents (ASRs) for research use
Reagent products provided for research applications; in some markets these are designated as research-use-only and not for in vitro diagnostic use.
Automated extraction and PCR setup platform (high-throughput)
Integrated platform for automated sample extraction and PCR setup with features for traceability, reduced reagent waste and a small laboratory footprint; supports high-density plate formats.
Automated result-calling software with LIS integration
Software that interprets PCR output, provides easy-to-interpret calls, prints reports and integrates with laboratory information systems; validated on common PCR instruments.
Multiplex pathogen detection kits (multiplex real-time PCR)
Kits that enable simultaneous detection of multiple infectious pathogen targets using multiplexed real-time PCR workflows compatible with the company’s nucleic-acid simplification method.
Sample processing kits and conversion reagent
Sample processing kits that lyse specimens and isolate nucleic acids (DNA and RNA), and a bisulphite-based conversion reagent used to simplify nucleic-acid sequences prior to PCR.
Analyte specific reagents (ASRs) for research use
Reagent products provided for research applications; in some markets these are designated as research-use-only and not for in vitro diagnostic use.
Automated extraction and PCR setup platform (high-throughput)
Integrated platform for automated sample extraction and PCR setup with features for traceability, reduced reagent waste and a small laboratory footprint; supports high-density plate formats.
Automated result-calling software with LIS integration
Software that interprets PCR output, provides easy-to-interpret calls, prints reports and integrates with laboratory information systems; validated on common PCR instruments.
Services
Development of laboratory protocols, access to performance materials and clinical samples, and on-site/regional training for customers and distributors.
Development of laboratory protocols, access to performance materials and clinical samples, and on-site/regional training for customers and distributors.
Expertise Areas
- Molecular diagnostics development
- Syndromic multiplex PCR assay design
- Reagent formulation and clinical kit manufacture
- Laboratory automation and workflow integration
Key Technologies
- Bisulphite-mediated nucleic acid simplification (3-base conversion)
- Multiplex real-time PCR (qPCR)
- Automated nucleic acid extraction and liquid handling
- High-throughput 384-well PCR workflows
News & Updates
Secured lab space and operations support at BioHub Birmingham to support protocol development, access to clinical samples, customer training and technical support in the UK/Europe.
A gastrointestinal parasite detection kit based on the company's nucleic-acid simplification and multiplex PCR workflow received FDA 510(k) clearance for sale in the United States.
Production team expanded since 2020 to meet increased demand (including COVID-19 related demand) and to support global supply requirements.
Secured lab space and operations support at BioHub Birmingham to support protocol development, access to clinical samples, customer training and technical support in the UK/Europe.
A gastrointestinal parasite detection kit based on the company's nucleic-acid simplification and multiplex PCR workflow received FDA 510(k) clearance for sale in the United States.
Production team expanded since 2020 to meet increased demand (including COVID-19 related demand) and to support global supply requirements.