G1 Therapeutics, Inc.


G1 Therapeutics is dedicated to developing and delivering next-generation cancer therapies aimed at improving the lives and outcomes of people living with cancer. As a subsidiary of Pharmacosmos Therapeutics, the company focuses on innovative treatments, including Trilaciclib, to address chemotherapy-induced myelosuppression and enhance immune responses in cancer patients.

Industries

biotechnology
developer-platform
medical
oncology
therapeutics

Nr. of Employees

medium (51-250)

G1 Therapeutics, Inc.


Products

Intravenous CDK4/6 inhibitor for reduction of chemotherapy-induced myelosuppression

An intravenously administered CDK4/6 inhibitor given prior to cytotoxic chemotherapy to reduce multilineage myelosuppression, preserve immune function, and decrease the need for supportive-care interventions.


Services

Design and conduct of Phase I–III clinical trials, translational studies, real-world evidence projects, and HEOR analyses to support therapeutic development.

Expertise Areas

  • Oncology clinical trial management
  • Myeloprotection strategies for chemotherapy
  • Immuno-oncology translational research
  • Pharmacokinetics and pharmacodynamics
  • Show More (4)

Key Technologies

  • CDK4/6-targeted kinase inhibition
  • Preclinical tumor models
  • T-cell and tumor immune profiling assays
  • PK/PD modeling and analysis
  • Show More (3)

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