Formulex
Formulex Pharma Innovations (est. April 2019) is an Israeli formulation and drug-delivery development company that provides formulation R&D, analytical support and small-scale GMP production for clinical-stage programs. The company focuses on solubility/bioavailability enhancement and new delivery routes for APIs across biopharma, nutraceutical and agrochemical applications, and supports formulation projects through analytical method development and stability programs.
Industries
Formulex
Products
Bioavailability-enhancing solid-dispersion platform
Spray-dried solid dispersions and submicron formulations designed to increase aqueous solubility and oral bioavailability of lipophilic drug substances.
Transmucosal and intranasal delivery compositions
Formulations for sublingual transmucosal absorption and intranasal powdered compositions optimized for mucosal permeability and targeted nasal/olfactory delivery.
Bioavailability-enhancing solid-dispersion platform
Spray-dried solid dispersions and submicron formulations designed to increase aqueous solubility and oral bioavailability of lipophilic drug substances.
Transmucosal and intranasal delivery compositions
Formulations for sublingual transmucosal absorption and intranasal powdered compositions optimized for mucosal permeability and targeted nasal/olfactory delivery.
Services
Formulation development services
End-to-end development of liquid and solid dosage forms for clinical trials, including design of immediate and modified release systems, topical/transdermal formulations, inhalation and mucosal delivery forms.
Analytical development and testing
Development and qualification of analytical and bioanalytical methods, dissolution and stability testing, impurity profiling, particle size and imaging analysis to support formulation and regulatory submissions.
GMP clinical manufacturing (small batches)
Production under GMP for clinical phases I and II for oral, topical and inhaled dosage forms, including process documentation and validation support.
Formulation development services
End-to-end development of liquid and solid dosage forms for clinical trials, including design of immediate and modified release systems, topical/transdermal formulations, inhalation and mucosal delivery forms.
Analytical development and testing
Development and qualification of analytical and bioanalytical methods, dissolution and stability testing, impurity profiling, particle size and imaging analysis to support formulation and regulatory submissions.
GMP clinical manufacturing (small batches)
Production under GMP for clinical phases I and II for oral, topical and inhaled dosage forms, including process documentation and validation support.
Expertise Areas
- Formulation development for clinical programs
- Analytical chemistry and bioanalysis (HPLC/LC‑MS, dissolution, impurity profiling)
- Bioavailability and solubility enhancement
- Drug delivery systems development (oral, sublingual, intranasal, inhalation, transdermal)
Key Technologies
- Spray-dried solid dispersions
- Submicron particle engineering
- Transmucosal (sublingual) formulations
- Intranasal powdered delivery for olfactory/brain targeting