FiteBac Dental
Developer of antimicrobial dental materials based on quaternary ammonium silane chemistry. The group formulates antimicrobial agents that can be covalently linked to polymerizable silane backbones and incorporated into dental materials (e.g., cavity cleansers, acrylics, adhesives, sealants). Activities shown on the site include in vitro and in vivo testing, randomized clinical trials, regulatory 510(k) submissions and at least one FDA-cleared dental cavity cleanser. Product R&D spans cavity cleansers, adhesives, sealants, endodontic irrigants/sealants and antimicrobial dental acrylics.
Industries
Nr. of Employees
small (1-50)
FiteBac Dental
Marietta, Georgia, United States, North America
Products
Antimicrobial cavity cleanser (topical dental cavity cleanser)
A dental cavity cleanser intended to clear carious debris and reduce dentally relevant microbes at restoration sites; described on the site as FDA-cleared.
Antimicrobial acrylic liquid (K18/MMA antimicrobial acrylic)
A K18-containing methyl methacrylate (MMA) liquid intended for incorporation into dental acrylics to provide contact-active antimicrobial activity.
Permanent acrylic-based dental adhesive (FT Bond)
A permanent acrylic-based adhesive formulation designed to include antimicrobial monomers to reduce biofilm formation and decay beneath restorations.
Orthodontic enamel sealant (CC Ortho-Seal)
Sealant containing antimicrobial additive intended for application to enamel prior to orthodontic bracket placement to reduce biofilm formation and white spot lesions.
Endodontic irrigant (UD Endodontic Irrigant)
Endodontic irrigant formulation in development intended to provide antimicrobial activity during root canal procedures.
Endodontic sealant (FT Endodontic Sealant)
Endodontic sealant under development incorporating antimicrobial monomers for root canal sealing applications.
Antimicrobial cavity cleanser (topical dental cavity cleanser)
A dental cavity cleanser intended to clear carious debris and reduce dentally relevant microbes at restoration sites; described on the site as FDA-cleared.
Antimicrobial acrylic liquid (K18/MMA antimicrobial acrylic)
A K18-containing methyl methacrylate (MMA) liquid intended for incorporation into dental acrylics to provide contact-active antimicrobial activity.
Permanent acrylic-based dental adhesive (FT Bond)
A permanent acrylic-based adhesive formulation designed to include antimicrobial monomers to reduce biofilm formation and decay beneath restorations.
Orthodontic enamel sealant (CC Ortho-Seal)
Sealant containing antimicrobial additive intended for application to enamel prior to orthodontic bracket placement to reduce biofilm formation and white spot lesions.
Endodontic irrigant (UD Endodontic Irrigant)
Endodontic irrigant formulation in development intended to provide antimicrobial activity during root canal procedures.
Endodontic sealant (FT Endodontic Sealant)
Endodontic sealant under development incorporating antimicrobial monomers for root canal sealing applications.
Services
Video demonstrations, technical summaries and resources for dental professionals illustrating antimicrobial technology applications and clinical use cases.
Collaboration with manufacturers to incorporate antimicrobial compounds into existing materials and product lines.
Collaboration on clinical trial design and execution to evaluate antimicrobial dental materials in vivo.
Video demonstrations, technical summaries and resources for dental professionals illustrating antimicrobial technology applications and clinical use cases.
Collaboration with manufacturers to incorporate antimicrobial compounds into existing materials and product lines.
Collaboration on clinical trial design and execution to evaluate antimicrobial dental materials in vivo.
Expertise Areas
- Antimicrobial dental materials
- Dental materials formulation
- Biofilm and antimicrobial testing
- Clinical trial design and execution
Key Technologies
- Quaternary ammonium silane chemistry
- Polymerizable silane functionalization
- Acrylic resin copolymerization
- PLGA nanoparticle formulation
News & Updates
Randomized clinical trial to determine in vivo antimicrobial efficacy of acrylic resin containing quaternary ammonium methacryloxy silicate (QAMS) using removable retainers to produce multi-species plaque biofilms. Trial identified on the site and linked to ClinicalTrials.gov (NCT02525458).
Peer-reviewed publication cited on the site reporting antibacterial and anti-proteolytic properties and collagen stabilization effects (Dental Materials. 2018).
Site states an FDA-cleared antimicrobial cavity cleanser is available.
Site states that a QAMS-copolymerized acrylic resin demonstrated contact-killing properties in vitro and has received US FDA 510(k) clearance for marketing.
Randomized clinical trial to determine in vivo antimicrobial efficacy of acrylic resin containing quaternary ammonium methacryloxy silicate (QAMS) using removable retainers to produce multi-species plaque biofilms. Trial identified on the site and linked to ClinicalTrials.gov (NCT02525458).
Peer-reviewed publication cited on the site reporting antibacterial and anti-proteolytic properties and collagen stabilization effects (Dental Materials. 2018).
Site states an FDA-cleared antimicrobial cavity cleanser is available.
Site states that a QAMS-copolymerized acrylic resin demonstrated contact-killing properties in vitro and has received US FDA 510(k) clearance for marketing.