FGH BioTech


FGH BioTech is a preclinical-stage biotechnology company focused on discovery and development of small-molecule therapeutics that modulate SREBP transcription factors and related lipid metabolism pathways for metabolic diseases and certain cancers. The company was founded in 2011 via an academic technology license and builds on decades of foundational research in fatty acid metabolism.

Industries

biopharma
biotechnology
health-care
pharmaceutical

Nr. of Employees

small (1-50)

FGH BioTech

Houston, Texas, United States, North America


Patents

Di-substituted pyrazole compounds for the treatment of diseases

US-11497738-B2

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Di-substituted pyrazole compounds for the treatment of diseases

US-11339142-B2

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Compositions of fatostatin based heterocyclic compounds and uses thereof

US-10328064-B2

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Products

Small Molecule Drugs Regulating SREBP Transcription Factors

Small molecule drugs developed to regulate SREBP transcription factors and related pathways for treating metabolic diseases and cancer.

Expertise Areas

  • Small-molecule drug discovery
  • Preclinical pharmacology and efficacy testing
  • Metabolic disease therapeutics (fatty liver, diabetes, cardiovascular risk)
  • Oncology therapeutics targeting lipid metabolism
  • Show More (2)

Key Technologies

  • Modulation of SREBP transcription factors
  • Small-molecule medicinal chemistry
  • In vitro biochemical and cell-based assays
  • Diet-induced and genetic mouse models
  • Show More (3)

News & Updates

Publication on the structural organization of animal fatty acid synthase.

Review or article discussing fatty acid metabolism as a target for metabolic syndrome.

Study reporting metabolic phenotype of ACC2 knockout mice.

Company founded in 2011 through a technology transfer license agreement from an academic institution.

A founding scientist was elected to the National Academy of Sciences.

Recognition listed among the founders' awards.


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