Enyo Pharma
ENYO Pharma is a clinical-stage biopharmaceutical company dedicated to developing highly differentiated therapeutics for improving the quality of life of patients with impaired kidney function. Their lead compound, Vonafexor, is in Phase 2 development for rare kidney disease Alport Syndrome and Chronic Kidney Diseases (CKD). The company focuses on fibrolytic and anti-inflammatory properties in organs such as kidney and liver, and also addresses liver-related infectious diseases like Hepatitis B and D.
Industries
Nr. of Employees
small (1-50)
Enyo Pharma
Patents
L-lysine salt of 4-chloro-5-[4-(2,6-dichlorophenyl)sulfonylpiperazin-1-yl]-1-benzofuran-2-carboxylic acid and various forms thereof
US-12030861-B1
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L-lysine salt of 4-chloro-5-[4-(2,6-dichlorophenyl)sulfonylpiperazin-1-yl]-1-benzofuran-2-carboxylic acid and various forms thereof
US-12030861-B1
View DetailsProducts
Oral small-molecule FXR agonist (lead clinical compound)
A synthetic non-steroidal small-molecule agonist of the farnesoid X receptor developed for oral once-daily administration; preferential tissue distribution to kidney and liver with reported fibrolytic and anti-inflammatory activity and ongoing Phase 2 clinical development for kidney and liver indications.
Oral small-molecule FXR agonist (lead clinical compound)
A synthetic non-steroidal small-molecule agonist of the farnesoid X receptor developed for oral once-daily administration; preferential tissue distribution to kidney and liver with reported fibrolytic and anti-inflammatory activity and ongoing Phase 2 clinical development for kidney and liver indications.
Services
Partnerships and licensing arrangements to advance therapeutic candidates through non-clinical and clinical development, and joint research collaborations with academic and industry partners.
Partnerships and licensing arrangements to advance therapeutic candidates through non-clinical and clinical development, and joint research collaborations with academic and industry partners.
Expertise Areas
- Clinical trial management (Phase 2)
- Nuclear receptor (FXR) small-molecule therapeutics
- Biomimetic drug discovery
- Bioinformatics and omics analysis
Key Technologies
- FXR (NR1H4) agonist pharmacology
- Small-molecule drug discovery
- Oral tablet formulation development
- Virus-host protein interaction analysis
News & Updates
ENYO Pharma sponsored and attended the 2022 International HBV Meeting organized by Dr. David Durantel in Lyon, France, from September 18-22, 2022.
ENYO Pharma announced a €39 million Series C financing and FDA clearance to advance Vonafexor in a Phase 2 clinical trial for patients with Alport syndrome.
ENYO Pharma sponsored and attended the 2022 International HBV Meeting organized by Dr. David Durantel in Lyon, France, from September 18-22, 2022.
ENYO Pharma announced a €39 million Series C financing and FDA clearance to advance Vonafexor in a Phase 2 clinical trial for patients with Alport syndrome.