Enquyst Technologies


Enquyst Technologies is an innovative bioprocess and analytical technology company founded in 2017, dedicated to developing disruptive equipment and processes to improve biotherapeutic manufacturing. Their mission is to create high-quality, cost-effective biological therapies accessible worldwide by leveraging patented IPP technology that enables continuous manufacturing and ultra-high purity bioproducts.

Industries

biotechnology
manufacturing

Nr. of Employees

small (1-50)

Enquyst Technologies

600 Suffolk Street, 2nd Floor, Lowell, MA 01854


Patents

Multichannel optical switch for in-line spectroscopic compound analysis

US-12546701-B2

View Details

Process technology for biological product manufacturing and downstream purification

US-11639367-B2

View Details

Process technology for biological product manufacturing and downstream purification

US-11566043-B2

View Details

Process technology for biological product manufacturing and downstream purification

US-11396526-B2

View Details

Process technology for biological product manufacturing and downstream purification

US-11345723-B2

View Details

Products

Isoelectric point-based flow-through purification system (resin-free downstream purification platform)

A modular flow-through purification system that isolates and polishes target biomolecules by leveraging isoelectric point, charge heterogeneity and size; designed for continuous operation, small footprint, closed sterile fluid paths and integrated in-line monitoring.


Services

Process development for purification and polishing of biologics across modalities, including experimental design, DoE, and scale-up feedback for equipment design.

Development, qualification and validation of bioanalytical and physicochemical assays for biomolecule characterization and in-process testing, including GLP-compliant documentation and SOP authoring.

Mechanical and electrical engineering services for design, prototyping, testing and iteration of bioprocess equipment, including fluidics, liquid handling and automated control integration.

Pilot-scale deployment and testing of continuous, resin-free purification workflows intended to replace multiple chromatography unit operations and reduce consumables and footprint.

Expertise Areas

  • Downstream process development
  • Continuous biomanufacturing
  • Process intensification for therapeutic proteins
  • Analytical method development and validation
  • Show More (6)

Key Technologies

  • Isoelectric point-based flow-through purification
  • Continuous downstream manufacturing platforms
  • Process Analytical Technology (in-line monitoring)
  • Tangential flow filtration (TFF) / UF-DF
  • Show More (7)

News & Updates

Enquyst Technologies was selected as a Top Innovator in Biotech and Dr. Jason Criscione presented the company’s innovative IPP technology to healthcare investors.

Dr. Jason Criscione, Chief Scientific Officer of Enquyst Technologies, presented at the new TechBio Showcase to provide an update on the company's innovative IPP technology and its impact on biologics manufacturing.

Dr Jason Criscione presented on the application of Enquyst’s IPP technology in the manufacture of viral vectors.

Enquyst was selected as one of twenty small-to-medium manufacturing companies to present a lightning pitch and poster showcasing its process analytical technologies.

Dr. Jason Criscione presented at Biotech Showcase to update on the company's IPP technology and its impact on biologics manufacturing.

Enquyst was selected to give a presentation at the Innovation Start-up Showcase at Bioprocess International 2023.

View All News

Similar organizations

Browse all ORGANIZATIONS

JOIN OUR MAILING LIST

Stay Connected with MTEC

Keep up with active and upcoming solicitations, MTEC news and other valuable information.