Elucid


Elucid is a Boston-based medical technology company using validated AI to provide physicians with a cost-effective means to optimize treatment decisions for patients with cardiovascular disease. Their platform offers ground-truth validated, non-invasive imaging analysis to quantify plaque characteristics, assess risk, and support personalized treatment plans, aiming to prevent heart attacks and strokes through advanced diagnostics and AI-driven insights.

Industries

analytics
biotechnology
medical-device
precision-medicine

Nr. of Employees

medium (51-250)

Elucid

2 Park Plaza, Suite 700, Boston, MA 02116


Products

CTA-based plaque analysis software (histology-validated)

Software that analyzes CT angiography to quantify plaque morphology and tissue types (lipid-rich necrotic core, calcification, non-calcified matrix, intraplaque hemorrhage) and produces clinician-facing reports and 3D visualizations. Documented validation against histopathology and peer-reviewed publications support analytic performance.

FFRct estimation software (CTA-based)

Software module that derives fractional flow reserve estimates from CTA-derived plaque and vessel metrics to assess lesion-specific ischemia without invasive catheterization.

Research edition with extended biomarkers (research-only features)

Extended software edition exposing additional research biomarkers (e.g., detailed intraplaque hemorrhage and fibrous cap/perivascular adipose tissue measures) for investigational use and study applications.


Services

Analytical service that processes CTA to quantify plaque composition and provide lesion- and vessel-level reports validated against histopathology.

Service to estimate lesion-specific fractional flow reserve from CTA-derived plaque and vessel measurements as a non-invasive ischemia assessment.

Support for investigator-initiated studies, registries, and industry-sponsored trials to provide imaging-derived endpoints, stratification, and longitudinal analysis for therapeutic evaluation.

Expertise Areas

  • Cardiovascular computed tomography image analysis
  • Quantitative imaging biomarkers and histology correlation
  • Non-invasive ischemia assessment (FFRct)
  • AI and machine learning for medical image tissue classification
  • Show More (4)

Key Technologies

  • Computed tomography angiography (CTA) analysis
  • Machine learning / neural networks for image tissue classification
  • FFRct estimation from imaging
  • Virtual transcriptomics (imaging-derived RNA expression)
  • Show More (5)

News & Updates

Jul 7, 2025 | Cardiac CT Expert to Advance Research and Commercialization of Company’s PlaqueIQ™ Image Analysis Software.

Mar 3, 2025 | Elucid has added several senior members to its clinical and commercial teams.

Nov 4, 2024 | Decision makes cardiovascular imaging technologies more viable for providers.

FDA 510(k) Clearance for PlaqueIQ™

Received FDA 510(k) clearance for its ground-truth validated plaque analysis software.

Series B Funding of $27 Million

Closed a $27 million Series B financing round to expand commercialization.

FDA and CE Mark Approval for PlaqueIQ™

First FDA-cleared and CE-marked software for non-invasive plaque quantification.


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