Elm Street Ventures


Seed and early-stage venture fund based in New Haven, CT, that primarily invests in companies with technology connections to Yale University. The firm focuses on translating university research into companies across therapeutics, advanced materials, green chemistry and climate-related technologies, and provides early capital, co-founding support, and ongoing portfolio guidance.

Elm Street Ventures

New Haven, Connecticut, United States, North America


Services

Seed and early-stage venture capital

Equity investments in seed and early-stage companies, typically focused on technologies originating from Yale and the New Haven region.

Co-founding and portfolio operational support

Hands-on support for company formation, technical development planning, and strategic guidance.

Expertise Areas

  • Early-stage venture investing
  • University-to-market technology transfer
  • Biotechnology and therapeutics commercialization
  • Materials commercialization and pilot manufacturing
  • Show More (4)

Key Technologies

  • Protein degradation therapeutics
  • Receptor-targeted small-molecule therapeutics (e.g., mGluR5 antagonists)
  • Targeted protein-based cancer mechanisms (RIPTAC-style modalities)
  • Tumor microenvironment-targeted delivery (low-pH targeting)
  • Show More (4)

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