DiFusion Technologies
Developer of immunomodulatory, load-bearing polymer implants combining a PEEK-derived polymer matrix with negatively charged hydrophilic zeolite ceramic additives. The company focuses on materials that modulate macrophage phenotype to support bone regeneration, preclinical evaluation (in vitro and animal models), biomechanical testing, and clinical outcome analysis. The biomaterial has received FDA 510(k) clearance in the USA.
Industries
Nr. of Employees
small (1-50)
DiFusion Technologies
Patents
Products
Hydrophilic PEEK-based composite spinal implant with negatively charged zeolite additive
A load-bearing spinal implant material composed of a PEEK-derived polymer matrix combined with negatively charged hydrophilic ceramic (zeolite) particles designed to support bony ingrowth and radiographic verification of fusion.
Hydrophilic PEEK-based composite spinal implant with negatively charged zeolite additive
A load-bearing spinal implant material composed of a PEEK-derived polymer matrix combined with negatively charged hydrophilic ceramic (zeolite) particles designed to support bony ingrowth and radiographic verification of fusion.
Services
In vitro assays and animal model studies to assess immunomodulation, bone formation, and inflammatory responses to implant materials.
Mechanical performance testing of implants (compression, torsion) to relevant ASTM standards and comparison to cortical bone properties.
Compilation and analysis of clinical radiographic outcomes and retrospective fusion study data to support clinical adoption.
Access to a scientific advisory network and partnerships with academic investigators for study design and interpretation.
In vitro assays and animal model studies to assess immunomodulation, bone formation, and inflammatory responses to implant materials.
Mechanical performance testing of implants (compression, torsion) to relevant ASTM standards and comparison to cortical bone properties.
Compilation and analysis of clinical radiographic outcomes and retrospective fusion study data to support clinical adoption.
Access to a scientific advisory network and partnerships with academic investigators for study design and interpretation.
Expertise Areas
- Immunomodulatory biomaterials
- Orthopedic implant materials and design
- Preclinical in vitro and animal evaluation
- Biomechanical and ASTM testing of implants
Key Technologies
- PEEK-based composite polymers
- Negatively charged hydrophilic zeolite (ceramic) additives
- Scanning electron microscopy (SEM)
- Macrophage polarization assays (M1/M2)
News & Updates
Press coverage summarizing comparative study results where the immunomodulatory composite biomaterial outperformed titanium or PEEK in selected assays and models.
Announcement of FDA 510(k) clearance for the biomaterial used in spinal implants.
Articles and commentary (AP News, Becker's Spine, Becker's Hospital Review) discussing preclinical and clinical findings for the material.
Recognition presented at a North American Society meeting (award mentioned in company materials and imagery).
Press coverage summarizing comparative study results where the immunomodulatory composite biomaterial outperformed titanium or PEEK in selected assays and models.
Announcement of FDA 510(k) clearance for the biomaterial used in spinal implants.
Articles and commentary (AP News, Becker's Spine, Becker's Hospital Review) discussing preclinical and clinical findings for the material.
Recognition presented at a North American Society meeting (award mentioned in company materials and imagery).