DeNovaMed


DeNovaMed is a pioneering pharmaceutical company dedicated to developing innovative antibiotics to combat bacterial infections and drug resistance. Their focus includes addressing serious health issues such as diabetic foot ulcers, bacterial infections, and antibiotic-resistant strains. The company leverages advanced drug design, computer-aided drug discovery, and a strong team of experts to create novel therapies with broad therapeutic potential. DeNovaMed aims to provide effective solutions to global health challenges posed by resistant bacteria and to lead in antibiotic innovation.

Industries

biotechnology
health-care
medical
pharmaceutical

Nr. of Employees

small (1-50)

DeNovaMed

Sir Charles Tupper Medical Building, Dalhousie University Suite 1A-1; 5850 College Street Halifax, Nova Scotia B3H 4H7


Patents

Diphenyl substituted thiophene-2-amide derivatives and pharmaceutical compositions thereof useful as antimicrobial

US-11306067-B2

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Antimicrobial/adjuvant compounds and methods

US-9012655-B2

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Expertise Areas

  • Antibacterial drug discovery
  • Computer-aided drug design (computational medicinal chemistry)
  • Novel mechanism-of-action development (lipid metabolism / ACP synthase targeting)
  • Preclinical development and lead optimization
  • Show More (6)

Key Technologies

  • Computer-aided drug design (de novo molecular modeling)
  • ACP synthase (AcpS) inhibition
  • De novo small-molecule library synthesis
  • Minimum inhibitory concentration (MIC) assays
  • Show More (5)

News & Updates

Research on the design and optimization of hundreds of novel compounds against ACP synthase, culminating in preclinical candidate DNM0547, published in Nature Communications.

Development of a new family of antibiotics to treat multidrug-resistant bacteria, addressing a major global health threat, with validation from peer-reviewed publication.

Issued Patents

DeNovaMed has over 6 issued patents related to their antibiotic compounds and technology.

Research Milestones

Development of novel antibiotics DNM0547 and DNM0904, with successful preclinical testing and publication in scientific journals.


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