DefenSight Pty Ltd and Adelaide University


DefenSight is an Adelaide-based imaging and analytics company that converts microscopy data into reproducible, per-cell evidence of pathogen activity and host-cell injury. The organisation develops interpretable, uncertainty-aware machine learning and validated imaging workflows to support biological threat characterisation, high-content screening, and operational decision‑making with onshore data residency and documented QC/validation pipelines.

Industries

Biotechnology Research

Nr. of Employees

small (1-50)

DefenSight Pty Ltd and Adelaide University

Rundle Mall, Adelaide, Hutt Street, Adelaide Bc, Sturt Street, Parliament House, Halifax Street, Station Arcade, City West Campus, South Australia, Australia


Products

Imaging and analysis pipeline (interoperable, interpretable)

A modular pipeline that standardises inputs, captures high-resolution imaging, performs per-cell segmentation and feature extraction, applies interpretable ML models, and delivers decision-ready structured outputs.


Services

End-to-end service where clients send fixed or inactivated samples; includes validated staining, image acquisition on confocal/super-resolution systems, per-cell analysis and reporting with methods text ready for publication.

Expertise Areas

  • Biological threat characterisation (host-response imaging)
  • High-content imaging analytics
  • Interpretable and uncertainty-aware machine learning
  • Assay qualification and validation
  • Show More (3)

Key Technologies

  • High-content fluorescence microscopy
  • Super-resolution microscopy (Airyscan, STORM)
  • Single-molecule imaging
  • Holotomography (label-free live imaging)
  • Show More (6)

News & Updates

Research agreement where the Flinders University Virology Laboratory runs infectivity assays on material imaged by the platform to provide independent biological validation.

Company secured its first commercial contract as it transitions from early-stage venture to commercial operations.

Selected to interview for CSIRO’s ON Accelerate 2026 deep-tech commercialisation accelerator following completion of ON Prime.

Finalist in Rising Star of the Year (SME) and Academic/Researcher of the Year categories.

Founder named finalist for AI Academic/Researcher of the Year for work on phenotypic signature extraction.

Company named a finalist in the Emerging Innovator category.


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