Day Zero Diagnostics


Day Zero Diagnostics is a Boston-based company pioneering infectious disease diagnostics using whole-genome sequencing and machine learning. Their mission is to revolutionize diagnosis and treatment of infectious diseases by providing rapid, comprehensive organism identification and antimicrobial resistance profiling without the need for culture, thereby enabling precision medicine and better outbreak management.

Industries

biotechnology
health-care
health-diagnostics
medical-device

Nr. of Employees

medium (51-250)

Day Zero Diagnostics

Boston, Massachusetts, United States, North America


Products

Sample preparation method for direct-from-blood pathogen sequencing

A laboratory method to enrich and recover pathogen genomes directly from blood samples to enable whole-genome sequencing without prior culture.

Computational platform for AMR prediction from whole-genome data

A software platform that analyzes pathogen whole-genome sequences and returns predicted antimicrobial susceptibility profiles using machine learning models trained on large genome–phenotype datasets.


Services

Rapid genomic outbreak analysis service

Laboratory and computational service that performs whole-genome sequencing and automated analysis to determine pathogen relatedness for suspected healthcare-associated infection outbreaks, with rapid turnaround intended to inform infection control decisions.

Genomic-based antimicrobial susceptibility prediction service

Computational service that uses whole-genome sequencing inputs and machine learning models to predict antimicrobial resistance and susceptibility profiles for clinical pathogens.

Expertise Areas

  • Infectious disease genomics
  • Antimicrobial resistance prediction
  • Outbreak detection and genomic epidemiology
  • Sample preparation for direct-from-sample sequencing
  • Show More (4)

Key Technologies

  • Whole-genome sequencing (WGS)
  • Long-read sequencing
  • Hybrid genome assembly (short + long reads)
  • K-mer based genomic comparison algorithms
  • Show More (4)

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