Curi Bio, Inc.
Curi Bio is a science-first organization dedicated to advancing drug discovery and human disease modeling through innovative 3D tissue models, biosystems, and AI/ML insights. They focus on structurally mature and predictive human engineered cardiac, skeletal muscle, and disease models, providing platforms, models, and services to improve workflow and screening predictivity in pharmaceutical research.
Industries
Nr. of Employees
small (1-50)
Curi Bio, Inc.
201 Elliott Avenue West, Seattle, WA 98119, USA
Patents
Products
Instrumented system for multi-well contractility measurement
An instrument and compatible plate system that captures contractile activity from engineered muscle tissues in a multi-well format for functional testing.
Video-based contractility analysis software
Software for automated extraction and high-throughput analysis of contractility metrics from tissue videos, with analytics features for visualization and interpretation.
Voltage and calcium imaging platform
Imaging workflows and analysis tools for measuring voltage and intracellular calcium dynamics in excitable cell models.
Mechanical stretch instrument (cell-stretching system)
Incubator-compatible systems that apply cyclic mechanical stretch to cell cultures and engineered tissues to support maturation and mechanobiology studies.
Nano-structured high-content culture plates
Patterned culture plates engineered to enhance structural maturation and enable high-content imaging of cardiac and skeletal muscle cultures.
Human cell and media kits for cardiac and skeletal muscle tissues
Kits or productized offerings that include human-derived cells and tissue-specific media formulations to support 2D and 3D tissue production and assays.
Instrumented system for multi-well contractility measurement
An instrument and compatible plate system that captures contractile activity from engineered muscle tissues in a multi-well format for functional testing.
Video-based contractility analysis software
Software for automated extraction and high-throughput analysis of contractility metrics from tissue videos, with analytics features for visualization and interpretation.
Voltage and calcium imaging platform
Imaging workflows and analysis tools for measuring voltage and intracellular calcium dynamics in excitable cell models.
Mechanical stretch instrument (cell-stretching system)
Incubator-compatible systems that apply cyclic mechanical stretch to cell cultures and engineered tissues to support maturation and mechanobiology studies.
Nano-structured high-content culture plates
Patterned culture plates engineered to enhance structural maturation and enable high-content imaging of cardiac and skeletal muscle cultures.
Human cell and media kits for cardiac and skeletal muscle tissues
Kits or productized offerings that include human-derived cells and tissue-specific media formulations to support 2D and 3D tissue production and assays.
Services
Custom development of in vitro assays and engineered tissue models tailored to client research objectives and preclinical endpoints.
Screening workflows using engineered tissue models and functional readouts to profile compound effects on safety, efficacy, and potency-related endpoints.
Collaborative discovery programs leveraging tissue platforms, analytics, and specialized cells/media to support target validation and lead selection.
Custom development of in vitro assays and engineered tissue models tailored to client research objectives and preclinical endpoints.
Screening workflows using engineered tissue models and functional readouts to profile compound effects on safety, efficacy, and potency-related endpoints.
Collaborative discovery programs leveraging tissue platforms, analytics, and specialized cells/media to support target validation and lead selection.
Expertise Areas
- 3D engineered cardiac and skeletal muscle models
- In vitro disease modeling for cardiac and neuromuscular disorders
- Contractility measurement and functional phenotyping
- Voltage and calcium imaging assays
Key Technologies
- 3D engineered heart and skeletal muscle tissues
- 2D cell-based functional assays
- Plate-based force/contractility measurement systems
- Video-based contractility analysis
News & Updates
Upcoming live webinar on June 18, 2025, discussing reproducibility and use cases of Mantarray tissues.
Awarded for rapid growth and innovation in technology.
Award for innovative leadership in biotech.
Recognition for SBIR/STTR program success.
Recognition for innovative products.
Recognition for Mantarray platform.
Upcoming live webinar on June 18, 2025, discussing reproducibility and use cases of Mantarray tissues.
Awarded for rapid growth and innovation in technology.
Award for innovative leadership in biotech.
Recognition for SBIR/STTR program success.
Recognition for innovative products.
Recognition for Mantarray platform.