Curare
Consulting firm focused on translational science and early clinical drug development. Services include strategic drug development planning, translational biomarker strategies, clinical pharmacology (dose selection and PK/PD analysis), regulatory interaction support and targeted training in pharmacokinetics. Team experience spans preclinical in vitro/in vivo pharmacology, first-in-human studies, proof-of-concept and pediatric development.
Industries
Nr. of Employees
small (1-50)
Curare
Liempde, Noord-Brabant, The Netherlands, Europe
Services
Advisory services to design customized clinical development plans and study designs aimed at efficient progression to clinical proof-of-concept and optimized probability of success.
Support in target and mode-of-action analysis, selection of translatable biomarkers and integration of preclinical data to improve clinical development success.
Services include PK/PD analyses, dose selection strategy, drug–drug interaction assessment, special population considerations and preparation of clinical pharmacology components of regulatory submissions.
Two-day basic pharmacokinetics course covering ADME, PK parameter concepts, parameter derivation, PK/PD use in development and ADME of therapeutic proteins.
Advisory services to design customized clinical development plans and study designs aimed at efficient progression to clinical proof-of-concept and optimized probability of success.
Support in target and mode-of-action analysis, selection of translatable biomarkers and integration of preclinical data to improve clinical development success.
Services include PK/PD analyses, dose selection strategy, drug–drug interaction assessment, special population considerations and preparation of clinical pharmacology components of regulatory submissions.
Two-day basic pharmacokinetics course covering ADME, PK parameter concepts, parameter derivation, PK/PD use in development and ADME of therapeutic proteins.
Expertise Areas
- Translational science and biomarker strategy
- Clinical pharmacology and dose finding
- Strategic drug development planning
- Early phase (first-in-human) study design
Key Technologies
- PK/PD modeling and simulation
- Physiology-based pharmacokinetic (PBPK) approaches
- In vitro and in vivo pharmacology
- In vitro–in vivo correlation (IVIVC)
News & Updates
Reported client repeat business rate greater than 90%.
Reported client repeat business rate greater than 90%.