Cornerstone Pharmaceuticals


Cornerstone Pharmaceuticals is dedicated to developing innovative cancer therapies that target the metabolic foundation for tumor growth and harness the immune system to treat hard-to-treat cancers. Their mission is to improve the lives of people with significant medical unmet needs through science stemming from renowned institutions and compassionate efforts.

Industries

biotechnology
clinical-trials
pharmaceutical

Nr. of Employees

small (1-50)


Patents

Therapeutic methods and compositions for treating pancreatic cancer using 6,8-bis-benzylthio-octanoic acid

US-11622950-B2

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Methods of treating leukemia using compositions containing bis(benzylthio)octanoic acid and ion pairs thereof

US-11065335-B2

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Methods for treating cancer using 6,8-bis (benzylthio) octanonic acid

US-10391177-B2

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Pharmaceutical compounds

US-10179796-B2

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Pharmaceutical formulations containing lipoic acid derivatives

US-10098955-B2

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Methods of treating myeloma and lymphoma using compositions containing an ion pair of a lipoic acid derivative

US-9872845-B2

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Products

Clinical-stage metabolism-directed small-molecule therapeutic

A clinical-stage small-molecule therapeutic designed to target mitochondrial and metabolic pathways in cancer cells; evaluated in multiple combination and indication-specific clinical trials and recognized by regulatory authorities with orphan-designation(s).

Pipeline of metabolism-directed oncology candidates

Portfolio of additional drug candidates at various preclinical and clinical stages focused on targeting cancer metabolic pathways, available for co-development or licensing.


Services

Evaluation of external research and assets for in-licensing; development and execution of joint drug development plans with inventors and institutions; pursuit of out-licensing or co-development arrangements for later-stage candidates and selected geographies.

Operational leadership and execution support for oncology clinical trials across phases, including multi-center coordination and progression to pivotal studies.

Management of physician-submitted expanded access requests through a standardized submission form and dedicated review contact to assess individual patient access to investigational therapies.

Expertise Areas

  • Clinical trial management and execution
  • Cancer metabolism-targeted therapeutics
  • Regulatory strategy and designation
  • CMC and manufacturing regulatory oversight
  • Show More (5)

Key Technologies

  • Mitochondria-targeting small-molecule therapeutics
  • TCA-cycle and mitochondrial metabolism inhibition
  • In vivo cancer models for efficacy testing
  • Combination therapy development
  • Show More (5)

News & Updates

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