Core Clinical


Provider of integrated imaging core lab, preclinical translational imaging, radiochemistry and radiopharmaceutical support, clinical adjudication, and eClinical (RTSM/IRT) services for drug development. Offers multi‑modality preclinical and clinical imaging, GMP-aligned radiotracer synthesis and QC, regulatory-grade dosimetry and tracer kinetics, automated image analysis and AI workflows, centralized independent reads and adjudication, randomized trial supply management and direct-to-patient logistics, and in‑house clinical imaging sites for early-phase studies. Also provides specialized preclinical oncology and radioligand therapy (RLT) support including tumor model development, biodistribution, IND‑enabling dosimetry, and efficacy studies.

Industries

health-care
medical
pharmaceutical

Nr. of Employees

small (1-50)

Core Clinical

Doylestown, Pennsylvania, United States, North America


Products

Vendor-neutral preclinical image analysis software

Image post-processing platform for multi-modality preclinical image analysis and quantitative workflows.

Image data management and visualization platform

Centralized image data storage, management and visualization platform for clinical and preclinical imaging datasets, supporting analysis workflows and integrations.


Services

Standardized image acquisition guidance, central image QC, blinded independent reads, reviewer network management and regulatory-ready imaging data for clinical trials.

Multimodality preclinical imaging, biodistribution, PK/PD and efficacy studies across small and large animal models with integrated radiochemistry support and advanced quantitative analysis.

GMP-aligned radiolabeling and tracer production for diagnostic and therapeutic isotopes, analytical QC and technology transfer to qualified manufacturing sites.

Saturation, competition, kinetic and internalization assays plus ex vivo occupancy and immunoreactivity testing for ligand characterization.

Independent event adjudication, charter and form development, source data collection and committee management supported by a validated electronic adjudication platform.

Cloud-enabled interactive response technology for randomization, inventory management, automated site resupply, adaptive designs and integrations with eClinical systems; support for direct-to-patient shipments.

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Expertise Areas

  • Clinical imaging core lab operations and centralized reads
  • Preclinical-to-clinical translational imaging and biodistribution
  • Preclinical radioligand therapy (RLT) and theranostic development
  • Radiochemistry and GMP radiotracer production
  • Show More (4)

Key Technologies

  • Positron emission tomography (PET)
  • Single-photon emission computed tomography (SPECT)
  • Magnetic resonance imaging (MRI)
  • Computed tomography (CT)
  • Show More (9)

News & Updates

Participation at a major hematology meeting (company event listing).

Participation at a major CNS clinical trials meeting (company event listing).

Case study describing rapid scaling of imaging services for a Phase 3 Alzheimer's trial.

Discussion of semi-automated segmentation and use of AI-derived quantitative PET data in clinical trials.

Reported radiochemistry experience including 900+ agents radiolabeled, support for 80+ IND submissions and access to a network of 300+ production centers.

Reported in-house imaging clinics supporting 500+ studies and over 80 approved radiotracer INDs, with combined clinical/lab/office space reported.

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