Computational Life
Computational Life is dedicated to transforming healthcare outcomes through advanced computational modeling. Specializing in cardiogenic shock management, regulatory support, and R&D advising, the company develops mathematical models that provide innovative solutions at the intersection of clinical care, regulatory strategy, and research development. Their approach combines expertise with cutting-edge technology to address complex healthcare challenges, aiming to improve patient outcomes, streamline regulatory processes, and accelerate medical research.
Industries
Nr. of Employees
small (1-50)
Computational Life
Wilmington, Delaware, United States
Products
Computational physiological modeling platform
A modular analytical platform that builds physiologically based digital representations of individuals to simulate treatment and disease dynamics for clinical, R&D, and regulatory use cases.
Altegos
Altegos is a robust analytical technology based on mathematical models capable of generating a digital twin of an individual, describing subject-specific whole-body physiology to interpret intricate interactions between therapeutic interventions and human physiology.
In-Silico Regulatory Support Modeling
In-silico modeling solutions to create detailed evidence and reports for notified bodies submission processes for drugs and medical devices.
Regulatory Support Services
A comprehensive suite of regulatory services designed to guide drug and medical device submissions through preliminary consultation, in-silico evidence generation, and compliant documentation support.
In-Silico Clinical Trials
Simulation capabilities offering a faster, more ethical, and cost-effective way to evaluate drug and device effectiveness and safety.
Clinical Scenario Modeling
Advanced modeling diving deep into individual or population studies to bring precision to clinical research and offer insights into patient responses and treatment efficacies.
Computational physiological modeling platform
A modular analytical platform that builds physiologically based digital representations of individuals to simulate treatment and disease dynamics for clinical, R&D, and regulatory use cases.
Altegos
Altegos is a robust analytical technology based on mathematical models capable of generating a digital twin of an individual, describing subject-specific whole-body physiology to interpret intricate interactions between therapeutic interventions and human physiology.
In-Silico Regulatory Support Modeling
In-silico modeling solutions to create detailed evidence and reports for notified bodies submission processes for drugs and medical devices.
Regulatory Support Services
A comprehensive suite of regulatory services designed to guide drug and medical device submissions through preliminary consultation, in-silico evidence generation, and compliant documentation support.
In-Silico Clinical Trials
Simulation capabilities offering a faster, more ethical, and cost-effective way to evaluate drug and device effectiveness and safety.
Clinical Scenario Modeling
Advanced modeling diving deep into individual or population studies to bring precision to clinical research and offer insights into patient responses and treatment efficacies.
Services
Model‑based predictive support to simulate treatment options and patient hemodynamic responses in cardiogenic shock.
Preparation of in‑silico evidence packages and reports aligned with regulatory guidelines to assist notified body submissions for medical devices and drugs.
Consulting services from project inception through in‑silico evidence generation, including integration with existing models and bespoke model development.
Model‑based predictive support to simulate treatment options and patient hemodynamic responses in cardiogenic shock.
Preparation of in‑silico evidence packages and reports aligned with regulatory guidelines to assist notified body submissions for medical devices and drugs.
Consulting services from project inception through in‑silico evidence generation, including integration with existing models and bespoke model development.
Expertise Areas
- Clinical decision support
- Cardiovascular hemodynamics modeling
- In‑silico clinical trial design
- Model validation and verification
Key Technologies
- Multiscale physiological modeling
- Digital twin of patient physiology
- In‑silico clinical trials
- Uncertainty quantification (UQ)
News & Updates
A scientific paper published in ASAIO Journal on the validation of a multiscale computational model for cardiogenic shock.
A research paper published in Bioimpacts on the function of arteries and veins during simulated cardiac arrest.
Presentations at ASAIO and ESAIO Congresses on the characterization of a multiscale model for cardiogenic shock.
Distributed medical intervention testing on a digitally simulated patient. PCT phase
A patent related to distributed medical intervention testing on a digital patient.
A scientific paper published in ASAIO Journal on the validation of a multiscale computational model for cardiogenic shock.
A research paper published in Bioimpacts on the function of arteries and veins during simulated cardiac arrest.
Presentations at ASAIO and ESAIO Congresses on the characterization of a multiscale model for cardiogenic shock.
Distributed medical intervention testing on a digitally simulated patient. PCT phase
A patent related to distributed medical intervention testing on a digital patient.