Cobra Biologics
Charles River Laboratories is dedicated to helping accelerate research and drug development, providing essential products and services from discovery to early development and manufacturing. Their purpose is to create healthier lives through world-class science and solutions, driven by a commitment to innovation, animal welfare, and responsible operation. They support clients across the entire drug development continuum with a focus on scientific and regulatory guidance, innovative methodologies, and next-generation technologies. The company emphasizes responsible science through its 4Rs (Replacement, Reduction, Refinement, and Responsibility), investing in new approach methods, digital technologies, and sustainable practices to reduce animal use and improve animal welfare. They are committed to responsible animal research, environmental sustainability, and fostering a culture of care, leadership, and collaboration.
Industries
Nr. of Employees
large (251-1000)
Cobra Biologics
Products
Virtual control group solutions
Data-driven virtual control groups that select animal candidates from historical data to replace or augment concurrent control arms in safety studies when scientifically appropriate.
Human intestinal organoid testing platforms
In vitro organoid models used for antiviral toxicity testing and early translational evaluation of candidate therapeutics.
3D cancer model services
Three-dimensional tumor organoid models and related screening services to support oncology discovery and preclinical evaluation.
Recombinant endotoxin detection reagents and microfluidic cartridges
Animal-free recombinant endotoxin reagents and cartridge-based microfluidic endotoxin testing products intended as alternatives to reagents sourced from natural materials.
Sentinel-free pathogen surveillance system
Environmental pooled-sample collection combined with PCR-based assays for vivarium health monitoring to reduce reliance on sentinel animals.
Virtual control group solutions
Data-driven virtual control groups that select animal candidates from historical data to replace or augment concurrent control arms in safety studies when scientifically appropriate.
Human intestinal organoid testing platforms
In vitro organoid models used for antiviral toxicity testing and early translational evaluation of candidate therapeutics.
3D cancer model services
Three-dimensional tumor organoid models and related screening services to support oncology discovery and preclinical evaluation.
Recombinant endotoxin detection reagents and microfluidic cartridges
Animal-free recombinant endotoxin reagents and cartridge-based microfluidic endotoxin testing products intended as alternatives to reagents sourced from natural materials.
Sentinel-free pathogen surveillance system
Environmental pooled-sample collection combined with PCR-based assays for vivarium health monitoring to reduce reliance on sentinel animals.
Services
Production, customization, and operational support for laboratory animal models including breeding, genotyping, and colony management to support basic research and preclinical studies.
End-to-end development and manufacturing services for cell and gene therapies, from early development and analytical testing through scalable GMP manufacturing and release testing.
Analytical, microbiological, and manufacturing support services for biologics across discovery, preclinical, clinical and commercial phases, including viral safety and cell line characterization.
Quality control services for sterility, bioburden and endotoxin testing using rapid detection systems, validated animal-free endotoxin assays, and cartridge-based microfluidic workflows.
Managed discovery services coordinating target discovery, hit identification, lead optimization, translational pharmacology and safety testing to reduce time to clinic.
Conduct of IND-enabling GLP and non-GLP studies, study design consultation, SEND-compliant reporting and preparation of regulatory submissions.
Production, customization, and operational support for laboratory animal models including breeding, genotyping, and colony management to support basic research and preclinical studies.
End-to-end development and manufacturing services for cell and gene therapies, from early development and analytical testing through scalable GMP manufacturing and release testing.
Analytical, microbiological, and manufacturing support services for biologics across discovery, preclinical, clinical and commercial phases, including viral safety and cell line characterization.
Quality control services for sterility, bioburden and endotoxin testing using rapid detection systems, validated animal-free endotoxin assays, and cartridge-based microfluidic workflows.
Managed discovery services coordinating target discovery, hit identification, lead optimization, translational pharmacology and safety testing to reduce time to clinic.
Conduct of IND-enabling GLP and non-GLP studies, study design consultation, SEND-compliant reporting and preparation of regulatory submissions.
Expertise Areas
- Preclinical safety assessment and toxicology
- Genetically engineered and humanized animal models
- Cell and gene therapy development and CDMO services
- Biologics analytical testing and quality control
Key Technologies
- Next-generation sequencing (NGS)
- Quantitative PCR (qPCR)
- Flow cytometry
- Organoids and 3D cell models